Sentences with phrase «cycle data by»

The (often faulty or misleading) use of these solar cycle data by «climate sceptics» has quite a pre-history, see e.g. Damon and Laut (2004).

Not exact matches

The twin aims of making billions of dollars by churning data for the box and producing important work for the wider world, it turned out, were not always part of the «virtuous cycle» envisaged by Doctoroff.

They hope to be able to amass enough data about women's menstrual cycles, sexual behavior, mood, and diet that they can help any woman know exactly when to conceive, warn her about early problems like potential endometriosis, and over time, promote better health care for women in general by collecting large amounts of information that hasn't been collected before.

As with all phones, data is entered by cycling through each key's letters and numbers.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Having donated $ 11m to the main pro-Cruz Super Pac, Keep the Promise I, Mercer is Cruz's top financier — and the largest individual donor to Super Pacs or outside groups during the presidential election cycle thus far, according to data compiled by the political transparency website Open Secrets.

The developments come as Facebook CEO Mark Zuckerberg is set to appear in Washington Tuesday for hearings on the data scandal, in which at least 87 million people had their information harvested during the 2016 election cycle by Cambridge Analytica, a British political consulting firm.

If one has the wisdom to question their beliefs by actually testing them against data, thinking carefully about valuations, and studying the course of market cycles across history, none of these points should be surprising.

Zelia Rosenzweig shares how she has focused on improving the pre-sales cycle by removing data silos and one - off reports to give the entire trial team better insight and access into new customer opportunities.

After increasing their policy rates by 125 basis points and 150 basis points respectively in the current cycle, market participants expect that the tightening cycles in both the UK and New Zealand are close to an end, although in both cases, recent inflation data have caused some participants to revise that assessment.

To help medical billing companies scale and grow their business by performing data entry and revenue cycle management tasks through clear cut processes, open communication, good quality work, meeting / exceeding client expectations AND excellent client relationship.

Volatility returned to the markets in a big way in early February after inflation data triggered fears of a faster rate - hike cycle by the Federal Reserve.

I created the above chart of IPOs for 1990 - 2016 using Univerisity of Florida's Jay R. Ritter's data, Prof. Ritter uses a tight definition of IPOs which I believe is more helpful for getting a sense of where we are in the current bull cycle by excluding some noise, «follow - on offerings, oil & gas partnerships or unit trusts, ADRs (9 offerings), REITs», etc..

By analyzing the use of biblical citations in the four most recent election cycles, Berlinerblau manages an historical analysis that is fresh enough to be present in most readers» minds yet has a sufficient track record to provide useful data.

For example, the data collected by the fleet management software can help determine the most cost - effective life cycle of a vehicle.

However, it remains under investigation by the US attorney's office for the work done in the 2009 cycle by its for - profit arm, Data & Field Services.

The «high note» to which Levitan is referring is actually the result of a combination of things, including the fact that the WFP was cleared of wrongdoing in connection with its for - profit arm, Data & Field Services, during the 2009 election cycle by the US attorney's office.

So far in the 2016 cycle, she has gotten $ 111,935 from GOP leadership PACs, according to FEC records and calculations drawn from FEC data by the non-partisan Center for Responsive Politics» opensecrets.org.

Male donors are also increasing their participation in the campaign finance system by some 60 percent this election cycle, with nearly 1 million men so far making a political contribution in a congressional race, compared with about 615,000 at this point in the 2016 cycle, according to the center's data.

At the time, the WFP was under investigation by the US attorney's office in connection with work done by its now defunct for - profit arm, Data & Field Services, in the 2009 election cycle, and then - state Attorney General Cuomo was running for governor on a platform that included an anti-corruption plank.

New York County (better known as the borough of Manhattan) was the source of $ 200.9 million in federal contributions during the 2008 campaign cycle, the highest total for any county in the United States, according to Federal Election Commission data compiled by the Center for Responsive Politics.

In the meantime, I hope my thesis work will address some equally interesting questions: how migration of barren - ground caribou impacts wolf movement, whether there is such a thing as the arctic wolf (currently listed «data deficient» by the Committee for the Status of Endangered Wildlife in Canada), whether arctic foxes migrate or just disperse, and how lemming cycles affect that decision.

Researchers from the Perelman School of Medicine at the University of Pennsylvania, in partnership with ORGANIZE — a non-for-profit organization based in New York which leverages health data to end the organ donor shortage by applying smarter technologies, utilizing social media, building more creative partnerships, and advocating for data - driven policies — The Bridgespan Group — a global nonprofit organization that collaborates with mission - driven leaders, organizations, and philanthropists to break cycles of poverty and dramatically improve the quality of life for those in need — and Gift of Life Donor Program — an OPO which serves the eastern half of Pennsylvania, southern New Jersey, and Delaware — evaluated the metrics and criteria used to measure OPOs across the country, and found significant discrepancies in how potential donors are evaluated and identified.

The data analysed in the study was processed using an advanced life - cycle assessment tool — SCEnAT — developed by Professor Lenny Koh, Director of the Advanced Resource Efficiency Centre at the University's Management School and co-author of the paper.

The computer modelling study by Dr. Richard Boyle and colleagues from Denmark, Germany, China and the UK, published in Nature Geoscience, links data from the fossil record to well established connections between the phosphorus and oxygen cycles.

And then, using data collected by other scientists on three predator - prey pairs — mink - muskrat, gyrfalcon - rock ptarmigan and phage - Vibrio cholerae — they show how their theory could explain unexpected population cycles.

By combining data from multiple studies, Zhang and his colleagues identified six major cycles of warm and cold phases from 1000 to 1911.

An analysis of GOME - 2 data published in April suggests that carbon - cycle models underestimate peak photosynthetic output by as much as 50 — 75 % in parts of India, China and the African Sahel, and by 40 — 60 % in the «corn belt» of the US Midwest, which accounts for more than 40 % of the world's maize (corn) production (L. Guanter et al..

A larger sixth planet, closer in mass to Saturn, also appears significantly in the data at a greater distance from HD 10180, but the study's authors note that the signal could be caused by a long - term magnetic cycle on the star rather than the tug of an orbiting planet.

By providing new data on how CO2 cycles through land and ocean plants, HIPPO will allow researchers to improve the accuracy of their climate models and reduce that uncertainty, Stephens said.

Veizer fails to discuss the key issue (namely, whether the data support the idea that the warming trend, rather than just the temporary dip, could be explained by solar cycle variations).

A team led by Markus Covert, assistant professor of bioengineering, used data from more than 900 scientific papers to account for every molecular interaction that takes place in the life cycle of Mycoplasma genitalium, the world's smallest free - living bacterium.

The mean insolation at Earth orbit is about 1366 W / m ^ 2; the peak - to - peak variation over the 11 year solar cycle is about 3 W / m ^ 2; the authors discuss two running averages derived from different satellite data sets and analysis derived by Willson and Mordvinov (2003) and Frohlich and Lean (1998) respectively.

The Institute is currently running on a Site License by Flowjo, a flow cytometry data analysis software package which offers a range of analysis platforms that includes compensation, cell cycle, proliferation studies and kinetics.

«EPA's proposal offers some welcome efficiencies by avoiding the need for industry to duplicate notifications that have been made in recent Chemical Data Reporting (CDR) cycles, using a simple notification form and using EPA's existing Central Data Exchange (CDX) reporting infrastructure.

Cell cycle studies also showed that inhibition of mTOR function by using rapamycin or inhibition of mTOR expression by using mTOR - specific siRNA induced cell cycle arrest as shown by a dose - dependent decrease of cell cycle S phase (data not shown).

This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism of action, KMT2D mutations of B - lymphoma cells promote malignant outgrowth by perturbing methylation of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual treatment with chidamide and decitabine enhanced the interaction of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action of chidamide and decitabine may interfere with the differentiation and / or viability of PTCL - NOS through a PU.1 - dependent gene expression program.

White 1997 finds sea surface temperatures change by 0.1 °C due to the 11 year solar cycle, looking at data from 1955 to 1994.

It is reasonable to expect that the research by space scientists using data from the Webb will produce significant advances in understanding the formation and evolution of the oldest stars in our universe, the life cycles of stars, the environmental composition of different exoplanets, and possibilities for living systems on planets circling other stars.

In the latest data provided by the Society for Assisted Reproductive Technology, there were 174,962 cycles in 2013, and 21 % (36,958) were couples under the age of 35.

Please note, that while the color coding produced by the monitor provides a convenient way to assess your fertility status, for women with highly irregular cycles, it may also be necessary to interpret actual reading data (in addition to looking at the color coding), to accurately determine your most fertile days in the cycle and when ovulation occurred.

If, by chance, you need to erase and reset your Daysy device, we explain below how to manage this so that you can get the most accurate, reliable data on your fertility cycle.

About Blog Envision empowers project leaders to drive better performance by helping teams capture & use project data in real - time, rapidly detect and resolve issues, & streamline reporting cycles.

In a series of seminars led by Harvard Graduate School of Education faculty Richard Murnane, Kathryn Boudett, and Elizabeth City, the group developed an eight - step Data Wise cycle as a means to help school leaders organize the work of school improvement around a process that has specific, manageable steps.

We analyzed test - score data and election results from 499 races over three election cycles in South Carolina to study whether voters punish and reward incumbent school board members on the basis of changes in student learning, as measured by standardized tests, in district schools.

They extended already long sales cycles for state and district data and assessment platforms by at least two years while buyers tried to figure out the implications of CCSS and the assessment consortia on the architecture and functionality of their statewide IIS platforms.

We found that the teachers who made the most gains in their classroom practice (as measured by the CLASS ™ observation tool) focused their conversations with mentors on classroom practice — following a cycle in which mentors observed teachers and collected data, interpreted the data with mentees in post-observation meetings, planned next steps together and kept in touch between monthly visits.

Tim and his colleague Mark Poole kicked - off the cycle by performing a short skit to help teachers see how not to respond to Youth Truth data.

That post was motivated by an email from Ed Johnson providing his initial review of the just released TUDA (Trial Urban District Assessment) data from the 2017 testing cycle.

Led by a nationally recognized educator, this intensive training focuses on improving every step of the instructional cycle, from breaking down standards and building the best CFAs to using data to plan meaningful interventions.