Bala et al., Combined climate and carbon -
cycle effects of large - scale deforestation, Proc.
The carbon
cycle effects of the geoengineering might delay that outcome in the ocean by a few years but wouldn't prevent those outcomes from occurring,» he said.
If it includes a requirement to consider the life -
cycle effects of greenhouse gases associated with the coal to be extracted, it might tip the scales against the new mine.
Not exact matches
There was a time when the Fed was so «neutral» in its
effect on the business
cycle that the average informed woman or man on the street did not know the name
of the Fed chairman.
«The cumulative
effect of interest rate hikes is going to begin mounting,» said Greg McBride, Bankrate.com's chief financial analyst, particularly on variable - rate loans such as credit cards, home equity lines
of credit and adjustable - rate mortgages, which could rise within one to two statement
cycles.
Chinese policy shifts may cause tectonic
effects, but one virtue
of their system is their big plans don't switch with each election
cycle.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant
cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the
effect of lowering prices or reducing the number
of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
These risks include, in no particular order, the following: the trends toward more high - definition, on - demand and anytime, anywhere video will not continue to develop at its current pace or will expire; the possibility that our products will not generate sales that are commensurate with our expectations or that our cost
of revenue or operating expenses may exceed our expectations; the mix
of products and services sold in various geographies and the
effect it has on gross margins; delays or decreases in capital spending in the cable, satellite, telco, broadcast and media industries; customer concentration and consolidation; the impact
of general economic conditions on our sales and operations; our ability to develop new and enhanced products in a timely manner and market acceptance
of our new or existing products; losses
of one or more key customers; risks associated with our international operations; exchange rate fluctuations
of the currencies in which we conduct business; risks associated with our CableOS ™ and VOS ™ product solutions; dependence on market acceptance
of various types
of broadband services, on the adoption
of new broadband technologies and on broadband industry trends; inventory management; the lack
of timely availability
of parts or raw materials necessary to produce our products; the impact
of increases in the prices
of raw materials and oil; the
effect of competition, on both revenue and gross margins; difficulties associated with rapid technological changes in our markets; risks associated with unpredictable sales
cycles; our dependence on contract manufacturers and sole or limited source suppliers; and the
effect on our business
of natural disasters.
As research on the uptake
of new products shows, marketing helps take customers through the earlier stages
of the communications
effects cycle until they are ready to try your product.
As credibility builds over time, monetary policy does not have to respond to every hint
of inflation, knowing that the small fluctuations in inflation over the course
of the
cycle will not have any permanent
effects.
But there is one element
of the old textbook
cycle which is both unpredictable and pervasive in its
effects — animal spirits.
This movement — both up and down — was part
of what helped insulate the economy from the
effects of this particularly large terms
of trade
cycle.
Meanwhile, extreme valuations imply the likelihood
of steep market losses over the complete
cycle, and also for poor S&P 500 total returns on a 10 - 12 year horizon, but valuations often have little
effect on near - term market behavior.
Likewise, the frightening or exuberant features
of any given business
cycle typically have little
effect on the very, very long - term stream
of cash flows that stocks actually deliver over time.
Despite risks that I fully expect to devolve into a roughly -65 % loss in the S&P 500 over the completion
of the current market
cycle, it's absolutely critical to distinguish the long - term
effects of valuation from the shorter - term
effects speculative pressure.
You might need to run the experiment for three score and ten years to get some idea
of the life -
cycle effects.
Meanwhile, it's important to understand how risk and return work over the course
of the market
cycle, and in particular, the
effect that compounding has on both returns and losses.
2) By extending the projection horizon by an extra market
cycle (~ 6 years - the current half -
cycle is quite long - in - the - tooth from a hisorical perspective) the
effect of mean reversion has a greater chance to dominate the occasional noise that emerges (e.g. during the tech bubble) over shorter horizons.
The
effect a shift back to uniformly favorable market internals would be to move us to a more neutral outlook, though we would maintain our expectation
of dismal full -
cycle and long - term outcomes.
While long - term and full -
cycle market outcomes are tightly determined by market valuations, the
effect of valuations on outcomes over shorter segments
of the market
cycle depends on the psychological preference
of investors toward speculation or risk aversion.
As seen in prior
cycles, changes in short - term interest rates alone had yielded little
effect on financial conditions, as buoyant risk sentiment strengthened equities, corporate bonds, as well as various forms
of «esoteric» investments.
During the second stage
of the
cycle the bad
effects of creating a flood
of new money to purchase foreign currency reserves and manipulate the exchange rate become apparent.
It's extremely important that in thinking about the full market
cycle, investors keep the
effects of compounding in mind.
Raising the growth rate
of the economy by 0.3 per cent (the difference between the underlying productivity growth rate in the 1990s
cycle and the average
of the earlier
cycles) makes little difference over a year or two; over a decade or two, however, the cumulated
effect on living standards is substantial.
A lot
of the news that's come out recently has had
effects on pricing, so I find myself checking the news
cycle continuously.
Rather than simplistic cause and
effect, there could be a
cycle / spiral where men affect religion, and religion affects men in a spiral that rages out
of control.
Even if God put in motion the process
of evolution and natural
cycles, we know that those natural
cycles have a cause and
effect that has nothing to do with the old testament version
of storm interpretation.
These tools help in breaking the addictive
cycle — drinking to anesthetize the
effects of previous drinking — and are another reason for AA's remarkable effectiveness.
For our purposes, the medical and psychiatric therapies may be divided into three categories according to their purpose: (1) those therapies that aid in the physical rehabilitation
of the person suffering from the
effects of an acute binge and / or prolonged excessive drinking over many years; (2) those that help to keep the addictive
cycle broken and thus maintain sobriety for sufficient time to allow other therapies to take
effect; (3) those that aim at lessening the alcoholic's personality problems — both those that contributed to the causation
of his addiction and those resulting from the interpersonal chaos
of progressive alcoholism.
No less than other stories in the Jacob
cycle, it reflects the background
of the patriarchal age — frictions between groups (Hamor and Jacob); a level
of sexual morality beyond the reach
of our judgment and in any judgment ennobled by the integrity
of Hamor and the love
of his son for Dinah; the effort on the part
of both families to
effect a peaceful settlement honoring the religious sensibilities
of the abused; the despicable violation
of the terms
of agreement by two
of Jacob's sons; and finally, in perfect consonance with the general character
of Jacob, his sharp rebuke
of his sons not on moral but on utilitarian grounds:
What would a day be in the Divine circadian
cycle of an omnimodal, omnipotent being, 24 hours, 24 billion years, 24 milliseconds??? Nowhere in the Bible coes it say that evolution does not exist within the living realm, but Simon Peter does say that to the I Am»... one day is as a thousand years, and a thousand years is as one day...» (the Bible DOES recognize the
effects of animal husbandry, which is a form
of artificially - induced evolution on livestock species, and narrates accounts
of Divine intervention to influence it, so you can not factually say that it is outside the realm
of Divine probability by biblical accounts, as Divine probability contains, by textbook definition, the sum
of the laws
of nature.
As Tiebout pointed out, the direct treatment
of the alcoholic's «runaway symptom» is essential, and it consists
of methods by which the
cycle of drinking to overcome the
effects of previous drinking is blocked.
On the other hand, any percipient with a slow response - time, relative to the
cycle - time
of the structure, will register a steady
effect due to the system (now perceived as a unit).
He is trapped in a vicious
cycle of drinking to overcome the
effects of drinking — the «squirrel cage»
of alcoholism.
It relies on ecological processes, biodiversity and
cycles adapted to local conditions, rather than the use
of inputs with adverse
effects.
Our EMS follows a plan - do - check - act (PDCA)
cycle, providing a road map for how we address the immediate and long - term
effects of our operations on the environment.
The research team, led by Glyn Howatson and Phillip G. Bell at Northumbria University in the U.K., conducted this double - blind, placebo - controlled study to identify the
effects of Montmorency tart cherry juice on recovery from a metabolically challenging exercise: prolonged, high - intensity
cycling.
, analyzed the factors to consider when buying bulk wines, talking about the
effect of cycles on the bulk market.
It relies on ecological processes, biodiversity and
cycles adapted to local conditions, rather thanthe use
of inputs with adverse
effects.
It relies on ecological processes, biodiversity and nutrients, energy and water
cycles adapted to local conditions, rather than on the use
of external inputs with adverse
effects.
He was interested in the interdependence
of all
of nature, including the
effect of the lunar
cycle on nature.
The
effect of cycling's doping scandals was arguably most damaging in the United States, however.
be safe expect the worst ie do nt raise your expectations now n then start yapping at September that we need a striker, dm etc... The side
effect of that is always becoming a WOB for a huge portion
of the season up until march when the team work their asses out, grabs seven wins in a row, finishes strongly, everyone's praising it as the best team from the turn
of the year, Mr Wenger buys (mostly comes free or cheap) a mediocre player, everyone is nuts over him n by October, we r fighting for the champions league spot and the
cycle continues like FOREVER......................
Obviously, crying a specific period
of time
of «cry it out» method has an inevitable
effect on the baby's sleeping
cycle so that your baby can adjust to falling asleep on his own.
Matt Driller, a researcher working for the Australian Institute
of Sport performed two studies to measure the
effects of compression garments on back - to - back 15 minute
cycling trails.
The
effects of stress on memory and the hippocampus throughout the life
cycle: Implications for childhood development and aging.
When we talk about the potential for Attachment Parenting (AP) to change the world, we are referring to a ripple
effect: Our children growing up to be compassionate and empathic, becoming parents who foster secure attachments with their children, whose children then grow up to repeat the
cycle of peaceful living both in and out
of the home.
The birds, pollinators, land mammals, and marine mammals in Massachusetts have already started feeling the
effects of climate change on their habitats and life
cycles.
This is likely due to the
effects of ovarian stimulation on the endometrial lining, making it a bit resistant to implantation in a fresh
cycle.
Moreover, fin - de-siècle Americans turned increasingly to science as the most credible authority, particularly in matters
of health and the human life
cycle.24 An
effect of this was the increased stature in society, whether self - generated or not,
of the medical community.