Sentences with phrase «cyclic nucleotides»

CNGs open after direct binding of cyclic nucleotides, cAMP, and cGMP.

Of particular significance was the development of chemical methods to convert highly polar signalling molecules like cyclic nucleotides, inositol phosphates, and phosphoinositides to membrane - permeant, bioactivatable derivatives («prodrugs»)(Schultz 2003; Laketa et al. 2009, Laketa et al. 2014).

Symposia VI: Nitric Oxide and Sympatho - vagal Regulation Researchers will discuss targeting cyclic nucleotides to rescue cardiac sympatho - vagal phenotypes in cardiovascular disease and the blood brain barrier and control of arterial pressure.

CNGB1 combines with CNGA1 to form the rod cyclic nucleotide gated channel.

Vincent «Vinnie» Manganiello, a pioneering leader in the field of cyclic nucleotide - mediated signaling, has died at age 76.

The increase, observed as early as 60 seconds after the addition of corticotropin - releasing factor, suggests that changes in the intracellular concentration of the cyclic nucleotide coincide with or precede the secretion of adrenocorticotropic hormone in response to corticotropin - releasing factor.

They found what they were looking for on the CNGA3 gene, which encodes a cyclic nucleotide channel and plays a key role in transducing visual signals.

These actions are specific for the sympathetic and parasympathetic neurotransmitters and for the two cyclic nucleotides, as phenylephrine, tyramine, choline, adenosine 5» - monophosphate and guanosine 5» - monophosphate do not inodify lysosomal enzyme release.

Enzyme Release from Polymorphonuclear Leukocyte Lysosomes: Regulation by Autonomic Drugs and Cyclic Nucleotides

To be active, PKG I needs a small compound called cGMP, a cyclic nucleotide, to bind to the R domain, which will then free the C domain to carry on phosphorylation of other proteins.

In both PKA and PKG, the R domains seem to contact each other through their cyclic nucleotide binding domains.

Among the top hits was a variant adjacent to the gene for PDE10A, a cyclic nucleotide phosphodiesterase involved in regulating smooth muscle contraction, including the muscles that surround the spleen.