Sentences with phrase «cycling program with»

A decade earlier, Elefant, who was blind, had created a New York tandem cycling program with Achilles International, which helps people with disabilities join running events.

After a quick lunch stop in Tekapo we start our cycle program with a quiet ride alongside a canal system with spectacular views of Mt Cook & the Southern Alps.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (tprograms; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (tPrograms (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (tprograms; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Her viewpoints on the show are likely to gain scrutiny as viewers watch whether she gels with the program's other co-hosts, who typically maintain a more liberal perspective on the news cycle.

Many factors could cause BlackBerry's actual results, performance or achievements to differ materially from those expressed or implied by the forward - looking statements, including, without limitation: BlackBerry's ability to enhance its current products and services, or develop new products and services in a timely manner or at competitive prices, including risks related to new product introductions; risks related to BlackBerry's ability to mitigate the impact of the anticipated decline in BlackBerry's infrastructure access fees on its consolidated revenue by developing an integrated services and software offering; intense competition, rapid change and significant strategic alliances within BlackBerry's industry; BlackBerry's reliance on carrier partners and distributors; risks associated with BlackBerry's foreign operations, including risks related to recent political and economic developments in Venezuela and the impact of foreign currency restrictions; risks relating to network disruptions and other business interruptions, including costs, potential liabilities, lost revenues and reputational damage associated with service interruptions; risks related to BlackBerry's ability to implement and to realize the anticipated benefits of its CORE program; BlackBerry's ability to maintain or increase its cash balance; security risks; BlackBerry's ability to attract and retain key personnel; risks related to intellectual property rights; BlackBerry's ability to expand and manage BlackBerry ® World ™; risks related to the collection, storage, transmission, use and disclosure of confidential and personal information; BlackBerry's ability to manage inventory and asset risk; BlackBerry's reliance on suppliers of functional components for its products and risks relating to its supply chain; BlackBerry's ability to obtain rights to use software or components supplied by third parties; BlackBerry's ability to successfully maintain and enhance its brand; risks related to government regulations, including regulations relating to encryption technology; BlackBerry's ability to continue to adapt to recent board and management changes and headcount reductions; reliance on strategic alliances with third - party network infrastructure developers, software platform vendors and service platform vendors; BlackBerry's reliance on third - party manufacturers; potential defects and vulnerabilities in BlackBerry's products; risks related to litigation, including litigation claims arising from BlackBerry's practice of providing forward - looking guidance; potential charges relating to the impairment of intangible assets recorded on BlackBerry's balance sheet; risks as a result of actions of activist shareholders; government regulation of wireless spectrum and radio frequencies; risks related to economic and geopolitical conditions; risks associated with acquisitions; foreign exchange risks; and difficulties in forecasting BlackBerry's financial results given the rapid technological changes, evolving industry standards, intense competition and short product life cycles that characterize the wireless communications industry.

Unlike other lead generation companies that might only provide lead generation outsourcing (many through international representatives), we provide U.S. based turnkey programs to cover every step of the sales cycle, with B2B lead generation services and support for qualifying business leads based on sound marketing principles.

Against that background, one might justifiably ask whether it makes sense to have one economy (the United States) in a tightening monetary policy cycle, while the other (eurozone) presses on with its more accommodative easing program.

We have helped companies with programs targeted at helping them improve execution throughout the Client Life Cycle.

Fox News set a record earlier in the month with 24 million people tuning in to the first Republican primary debate of the 2016 election cycle, making it the most - watched cable telecast of all time, excluding sports programming.

The underlying assumption behind all the models in this chapter is that a congregation has an exciting possibility and responsibility to create a comprehensive marriage and family nurture program, beginning with remote preparation for marriage and extending through all the changing seasons of the life cycle of a family.

An anti-doping group is saying they have «insurmountable» evidence of Armstrong's involvement with a very sophisticated doping program during his cycling career.

The Initiative funded a number of programs such as: the Soil Not Oil International Conference, the Story of Soil video, and the Carbon Farming Tour to San Francisco Bay Area farms with the Carbon Cycle Institute.

This research stream, which is primarily conducted within ARS's National Program on Quality and Utilization of Agricultural Products, is reviewed / renewed in five - year cycles, with the next cycle starting in 2015.

With the addition of Oregon, NICA now has the infrastructure in place to serve just over 60 % of the country's population; we are well on our way towards fulfilling our mission of providing every American teenager the opportunity to participate in NICA programming through a school or community based cycling team.»

Minnesota convinced so many kids who would have had spots at more successful programs later in the cycle to instead stick with them and sign early.

Due to the fact that our diffuser is extremely powerful and diffuses only pure essential oils, we have programmed our device with a «Usage Cycle» built into the unit.

GOOD + Foundation ™ partners with a national network of leading programs to break the cycle of family poverty through the power of donated goods and services.

We do not have statistics specifically for the health of infants from our own programs, but the published reports have suggested that frozen embryo transfer cycles in general are associated with reduced risks of low birthweight, very low birthweight, small for gestational age, pre-term birth, antepartum hemorrhage, placental abruption, perinatal mortality, and pre-eclampsia.

Program washer to the longest wash cycle (heavy duty) with hot water wash.

This off - off - year election cycle presents the perfect opportunity to pilot such a program in at least VA and NJ, and in doing so, train the first set of new digital organizers with whom to rebuild the bench.

We urge the Administration and legislature to work with business and other stakeholders to develop this program during the current budget adoption cycle.

Bicycle Sundays, a Westchester County Parks program, is sponsored by Con Edison, New York Presbyterian Hospital, the Westchester Parks Foundation and Danny's Cycles, with support from WHUD.

``... with regards to the sales transactions on the market daily, weekly, monthly or annually as the program involves continuous sales, a cycle of sales and re-stock until one decides to quit or terminate the cycle.»

«After last year's incredibly successful Participatory Budgeting process in the 38th District, with the highest number of participants in the City, it is my pleasure to re-launch this program for the coming budget cycle!»

We have made a major breakthrough to end this cycle of failure by partnering with Catholic Charities, Buffalo Public Schools and the Say Yes program.

During the application cycle for the 2018 - 19 fellowship year, we are hosting a series of live chats with fellows in various disciplines and career stages to share their insights and answer your questions about the program.

The University of Michigan Program in Biomedical Sciences will stop requesting GRE scores starting with next year's admission cycle

Some of the new nuclear science research programs, including the one at MIT, are studying new reactor designs and fuel cycles that scientists (and policy - makers) hope will make nuclear plants safer and cheaper to operate, and produce waste materials with smaller volume, shorter half - lives, and less appeal to terrorists and other would - be nuclear powers.

The budget cycle begins with the president's annual budget proposal outlining White House spending requests for each federal agency and program.

Researchers from the Perelman School of Medicine at the University of Pennsylvania, in partnership with ORGANIZE — a non-for-profit organization based in New York which leverages health data to end the organ donor shortage by applying smarter technologies, utilizing social media, building more creative partnerships, and advocating for data - driven policies — The Bridgespan Group — a global nonprofit organization that collaborates with mission - driven leaders, organizations, and philanthropists to break cycles of poverty and dramatically improve the quality of life for those in need — and Gift of Life Donor Program — an OPO which serves the eastern half of Pennsylvania, southern New Jersey, and Delaware — evaluated the metrics and criteria used to measure OPOs across the country, and found significant discrepancies in how potential donors are evaluated and identified.

In the new study, Narula, Igoshin and collaborators set out to explain how B. subtilis times its sporulation decision with its cell - division cycle, a programmed series of events that cells normally follow to reproduce.

Whatever the outcome of the first doping case stemming from the passport program, cycling has at least begun to restore its credibility with the anti-doping movement — WADA has been fiercely critical of the UCI's efforts in the past.

«With modest success in the technology management program, these cycles could compete with combined - cycle natural gas turbines and carbon capture and storage,» Dennis sWith modest success in the technology management program, these cycles could compete with combined - cycle natural gas turbines and carbon capture and storage,» Dennis swith combined - cycle natural gas turbines and carbon capture and storage,» Dennis said.

Study authors suggest that breaking the cycle of transmission of drug - resistant TB requires a greater focus on infection control efforts — while also maintaining global programs to quickly detect and effectively treat all people with TB.

From 1990 to the formation of NEI in 1994 he was the Vice President of Technical Programs at the U.S. Council for Energy Awareness (USCEA) where he was responsible for ensuring the technical accuracy and effectiveness of USCEA's industry communications and also led the regulatory, policy and R&D activities associated with supporting companies in the front - end of the nuclear fuel cycle.

Met mRNA was expressed rhythmically during the reproductive cycle, with peak mRNA accumulation just prior period of oocytes programming of sex.

Altieri and his team are currently focused on three programs to understand the biology of survivin with respect to cell cycle progression, in particular, mitosis, cell survival and the cellular stress response and how exploiting these pathways may provide new cancer therapeutics.

This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism of action, KMT2D mutations of B - lymphoma cells promote malignant outgrowth by perturbing methylation of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual treatment with chidamide and decitabine enhanced the interaction of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action of chidamide and decitabine may interfere with the differentiation and / or viability of PTCL - NOS through a PU.1 - dependent gene expression program.

The Institute's Hubble Mission Office has initiated a pilot, ultra-low priority SNAP program (14840, PI: Bellini) in Cycle 24, with the goal of taking useful data in Hubble orbits that absolutely no other program is able to use.

As part of a Head in the Clouds program with AWS, Cycle Computing, and Intel, NASA is leveraging cloud computing to study the carbon stored in trees and bushes over the Sahara.

In my #aabikinibody program, we help women get off the harmful, restrictive binge cycle and find a balance with eating.

A group of sport scientists from Baylor University recently did a study on 20 students with solid weight training experience and made them follow an identical lifting program for 4 weeks, followed by a two - week layoff, after which they went through another four - week training cycle.

With the RPT program outlined above, enough calories to sustain muscle growth, and the cycling of carbohydrates, you have the tools needed for sizable strength gains.

In Moon Club, our monthly guided ritual program to help you sync with the moon's cycles and supercharge your life, we took the time to chat with feminist venture capitalist Kimmy Scotti, who reminded us of the entrepreneurial power we have to shift the whole collective by thinking BIG and BOLD.

Circle + Bloom Natural Cycle for Fertility Mind - Body Program is an effective tool to help you take an active role in reducing the anxiety and stress associated with dealing with a fertility health issue, undergoing a fertility treatment and trying to get pregnant.

You were, prior to undertaking the Flo Living program, on medications for acne and cycle issues — what has been your journey with this?

Whichever program you choose, follow it up with intensive sprinting, cycling, rowing.

A well structured program with varied cycles and a long term plan will help you get the results you are hoping to achieve

The Ayurvedic Woman is a 3 Part Program that enables you with the power of Ayurvedic Knowledge to experience symtom - free health with a smooth menstrual cycle and a painless, graceful transition through menopause.

Holistic Natural Residential Weight Loss Programs for permanent weight loss consisting of improving eating, sleeping and exercise habits with regular schedules, addressing the underlying emotional issues, such as self - esteem, loneliness and boredom, restoring the natural hormonal hunger satiety cycle, and educating patients about shopping and food preparation.