Sentences with word «cyclosporin»

A systematic review and meta - analysis of the efficacy and safety of cyclosporin for the treatment of atopic dermatitis in dogs.

The interaction could be blocked either by adding cyclosporin A or a non-immunosuppressive analogue of it.

Other immunosuppressive drugs such as cyclosporin which allows for the use of less steroid but is a powerful drug that absolutely affects the patient's immune system.

Our vet has discouraged surgery and has put my dog on cyclosporin for a month.

Tanaka Y, Sato Y, Takahashi D, Matsumoto H, Sasaki T: Treatment of a case of feline infectious peritonitis with cyclosporin A. Veterinary Record Case Reports 2015, 3: e000134

These proteins were originally discovered as cellular receptors for immunosuppressive drugs, including cyclosporin A and FK506.

Tear flow over the eye can be increased using cyclosporin ophthalmic drops or corrective surgery.

The exact mechanism by which Cyclosporin or Tacrolimus increases tear production is not fully understood.

In higher doses cyclosporin causes cancer, but veterinarians have yet to document increased cancer risks in dogs placed on lower doses for itching.

I am being told that she will need to use cyclosporin drops for life now.

In certain cases the frequency of artificial tear therapy can be reduced or even discontinued once the full effects of Cyclosporin have been realized.

What changed the scene was an immunosuppressant molecule called cyclosporin, developed by researchers at Sandoz, the Swiss pharmaceutical company.

Scientists immediately wondered whether the HIV protein gag was mimicking cyclosporin A and affecting calcineurin.

On the one hand, we design and synthesize analogues of drug molecules (e.g. cyclosporin, rapamycin, paciltaxel) and combinatorial chemical libraries (addressable peptide arrays and DNA - encoded chemical libraries).

Answer: Cyclosporin ointment seems to work a lot better than OTC products like artificial tears.

When Cyclosporin is administered topically onto the eye, tear production will significantly improve in about 80 % of all cases depending on the cause of KCS.

Vet has given my cat cyclosporin for stomatits.

These artificial tears are usually used in conjunction with drugs such as Cyclosporin or Tacrolimus.

What it is: The drug is taken by organ recipients to inhibit rejection, allowing patients to take lower doses of cyclosporin, a more toxic immune suppressant.

In earlier research Yan reported that cyclosporin D, a drug used to treat patients with organ transplants and autoimmune diseases, prevents amyloid - beta proteins from injuring mitochondria.

«Doctors realized that with cyclosporin, you did not need a related donor,» says Lawrence Cohen, an anthropologist at the University of California at Berkeley.

Those medications include cyclosporin (Atopica ©), given to cats to help control skin allergies, eosinophilic granuloma or to prevent organ rejection.

However, similar to cyclosporin A, which here was used as transporter inhibitor, also other chemical compounds, including man - made pollutants, inhibit Abcb4 function and thus cause increased sensitivity of fish embryos to toxicants.

That raised an intriguing question, because one of the few things scientists already knew about cyclophilin A was that it is the target of a powerful immunosuppressant drug, cyclosporin A.

Co-authors of the study, «Sirolimus (SRL) Blunts Mitogen Response at Trough (C0) Levels More Than Cyclosporin (CSA) or Tacrolimus (TAC): A Safeguard for Our Many Long Term Noncompliant Kidney Transplant Patients (KTPs)» include UC San Diego School of Medicine physicians Nitin Khosla M.D., and Rodolfo Batarse, M.D., assistant professor of medicine.

Specific targets are Transplantation / immunosuppression (cyclosporin, tacrolimus, MMF), Oncology (paclitaxel, docetaxel, tamoxifen), Pain (morphine, tramadol), Psychiatry (antidepressants, antipsychotics), HIV (efavirenz, nevirapine) and Anticoagulation (coumarins).

Cell samples (2.5 × 105 cells / mL) were treated with rhodamine - 123 (1.3 μmol / L; Sigma - Aldrich) in the presence or absence of cyclosporin A (5 μmol / L; Sigma - Aldrich) for 90 min at 37 °C.

Cyclosporin by itself can be curative, or it might need to be given on and off as the disease waxes and wanes.

Therapy for canine atopic dermatitis involves topical antipruritic therapies, parasiticides, antihistamines, fatty acids, glucocorticosteroids, allergen specific immunotherapy and cyclosporin.

Cyclosporin (Atopica) is an immuno - modulating drug that can significantly reduce symptoms.

Cyclosporin, sold as Atopica, is the same drug that people take to prevent organ transplants rejection.

This means steroids in high doses and other drugs such as azathioprine, cytarabine, mycophenolate, cyclosporin, and cyclophosphamide.

Many cats need long - term corticosteroids or other immunosuppressive drugs such as cyclosporin.

Treatment could include allergy shots to desensitize your cat to the problem (allergen specific immunotherapy), and the use of medications such as cyclosporin, glucocorticoids, antihistamines.

Other treatment options can include interferon and cyclosporin to help block the immune system's attack on the tissue and laser therapy to help with healing and irritation, but these options still remain palliative at best.

Medicines containing levonorgestrel may increase the risk of cyclosporin toxicity due to possible inhibition of cyclosporin metabolism.