Sentences with phrase «cystic fibrosis patients»

Bacteria can stick together to form slimy sheets called biofilms that yellow people's teeth, line the lungs of cystic fibrosis patients and often resist antibiotics.

Lead UK author on the study, Professor Stuart Elborn, Dean of the School of Medicine, Dentistry and Biomedical Sciences at Queen's University Belfast, said: «The estimations we have made show very positive news for cystic fibrosis patients as the average survival age is increasing.

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In addition, clinicians have long known that cystic fibrosis patients with stable lung function who do not lose weight are more likely to live longer.

In lab experiments using tissue samples cultured from cystic fibrosis patients, scientists at the UNC School of Medicine and the UNC Marsico Lung Institute have shown that a new CF drug counteracts the intended beneficial molecular effect of another CF drug.

Professor Pierre - Régis Burgel, an author of the study from Cochin Hospital, Paris, said: «The estimations we have made show very positive news for cystic fibrosis patients as the average survival age is increasing.

Since 1986, we've been there to help cystic fibrosis patients along with their families and healthcare providers.

The 65Roses team is a group of individuals who run and raise money to financially assist cystic fibrosis patients cared for at the Augusta University Cystic Fibrosis Center.

The 65Roses team runs and raises money to assist cystic fibrosis patients cared for at the Augusta University Cystic Fibrosis Center.

Since 1986, we've been there to help cystic fibrosis patients along with their families and healthcare providers.

«We are now exploring ways to reformulate antibiotics together with relevant vitamins for delivery into cystic fibrosis patients and assess their efficacy, so that patients can benefit from these findings.»

But their study of 45 cystic fibrosis patients showed that when the respiratory tract contains a more diverse community of microbes, the patient is less likely to harbor Pseudomonas aeruginosa, a key pathogen associated with later stages of cystic fibrosis.

«This is an exciting and potentially life - changing finding, particularly relevant for cystic fibrosis patients who are chronically infected with multi-resistant bacteria.

The scientists performed the tests in a laboratory setting using 100 different bacterial strains isolated from the lungs of pediatric cystic fibrosis patients of Seattle Children's Hospital and 42 bacterial strains isolated from hospitalized adult patients at UPMC.

In the Netherlands, based on research reported in 2016 in Science Translational Medicine, Clevers and colleagues are already using personalized gut organoids, derived from rectal biopsies, to test whether cystic fibrosis patients will benefit from available drugs.

Cystic fibrosis patient Els van der Heijden received a new drug combination based on organoid tests.

«Multi-drug resistant infection spreading globally among cystic fibrosis patients.»

Elder «was diagnosed with cystic fibrosis when he was eight years old, at a time when most cystic fibrosis patients were only expected to live to early adulthood,» according to a White House statement.

«While cystic fibrosis patients are our initial target and a very high - priority target, we also could look at infections associated with burns or indwelling medical devices, such as venous catheters.

In the room were various patients, from Elana Simon, a young survivor of a rare liver cancer who has helped sequence her cancer type, who introduced the president; to towering former basketball great Kareem Abdul - Jabbar, who apparently takes targeted therapy for his leukemia; and cystic fibrosis patient William Elder, a 27 - year - old medical student and guest at the State of the Union address who takes a new drug aimed at the genetic flaw underlying his form of the disease.

New research comparing cystic fibrosis patients in the United States and Canada showed that, although the patients» nutritional status and lung function improved in both countries over the period from 1990 to 2013, the rate of improvement was faster in the United States.

For example, organoids grown from the guts of individual cystic fibrosis patients are used to predict their response to drugs.

Persistent bacterial infections pose serious health problems for humans, including Cystic Fibrosis patients.

That's why cystic fibrosis patients often get infections.

When the health of a young cystic fibrosis patient worsened, she underwent a double lung transplant and, only a year and a half later, she was winning medals at the World Transplant Games Federation for swimming.

My dream job is to work with other cystic fibrosis patients as a Registered Dietitian Nutritionist (RDN) to help them gain weight so that they can live a longer, healthier life.

That raises the possibility of using them to treat infections caused by biofilms, such as the Pseudomonas aeruginosa infections that often affect the lungs of cystic fibrosis patients.

The findings help explain why lung infections in cystic fibrosis patients are so hard to treat.

When they tested chemicals that inhibit DGKi in lung cells from cystic fibrosis patients, the scientists discovered that it appears to be a very promising drug target.

One runner, James Mathis, raised $ 7,295 in donations and in - kind gifts to help cystic fibrosis patients.

It could offer major benefits to cystic fibrosis patients with fungal infections in their lungs.»

The bacteria in this study, Pseudomonas aeruginosa, frequently cause pneumonia in hospital patients and life - threatening infections for cystic fibrosis patients and people with HIV and chronic wounds.

It's not hard to see a scenario where the pharma lobby enlists an outraged parent of a cystic fibrosis patient to decry government overreach that restricts patient choice.

The finding supports the notion of adding a base (a substance with higher pH) to certain inhaled treatments that can be given along with antibiotics, for example in cystic fibrosis patients.

Staphylococcus aureus and Pseudomonas aeruginosa commonly co-infect wounds, catheters and lungs of cystic fibrosis patients.

He examined Pseudomonas aeruginosa, a microbe that inhabits the mucus clogging the airways of cystic fibrosis patients.

Although scientists first mapped the genetic structure of P. aeruginosa 15 years ago, efforts to pinpoint how it behaves during an infection and which genes would need to be turned off to stop its spread have been hampered in part by the difficulty of mimicking the unique conditions of a cystic fibrosis patient's lungs.

Once limited to burn wounds, P. aeruginosa now causes severe hospital - acquired infections and persistent lung infections in cystic fibrosis patients.

Senior co-author Dr Alastair Innes from Western General Hospital, Edinburgh, UK adds, «Publication of this trial is a landmark for cystic fibrosis patients and we are particularly grateful to the many patients across the UK who gave their time and effort to participate and make this collaborative venture a success.»

Substances produced by a harmful bacterium in the lungs of cystic fibrosis patients may enhance the growth of other bacteria that, in turn, inhibit the harmful bacterium's biofilm, according to new research.

Substances produced by a harmful bacterium in the lungs of cystic fibrosis patients may enhance the growth of other bacteria that, in turn, inhibit the harmful bacterium's biofilm, according to new research published in PLOS Pathogens.

These findings suggest a potential mechanism by which S. parasanguinis, which is normally found on the surface of teeth, might colonize the lungs of a cystic fibrosis patient and inhibit P. aeruginosa.

Although Kalydeco has so far been approved only for 4 per cent of cystic fibrosis patients, who carry a specific mutation, the three drugs together could treat more than 90 per cent of people with the disease.

He benefits from a medication that targets the underlying cause of the disease for a small subset of cystic fibrosis patients.»

To make these cracks, the researchers turned to Pseudomonas aeruginosa — a bacterial species that often builds biofilms within the lungs of cystic fibrosis patients, which can lead to chronic obstructive pulmonary disease and subsequently death.

You stop taking the treatments, and 99.5 percent of the time, a cystic fibrosis patient on any given day will be fine.

Dental plaque may be the best - known example of a biofilm, but these slimy aggregates of bacteria also play major roles in such chronic infections as those in the urinary tract or in the lungs in cystic fibrosis patients.

«As a result of studying these proteins, we discovered novel structures that turn out to work very well against bacterial infections, including the complicated bacterial populations in lung infections in cystic fibrosis patients.»

How do microbes duke it out in the lungs of cystic fibrosis patients?