Sentences with phrase «cystic fibrosis transmembrane conductance regulator»

CF is caused by a defective gene that creates a protein called cystic fibrosis transmembrane conductance regulator (CFTR).

Though every CF patient carries mutations in both copies of the same gene — coding for a protein called cystic fibrosis transmembrane conductance regulator or CFTR — symptoms can vary widely from patient to patient.

Cystic fibrosis is a rare inherited disease caused by mutations in a single gene called cystic fibrosis transmembrane conductance regulator (CFTR) and affects 1 in every 2500 newborns in the UK and over 90000 people worldwide.

It is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) protein.

Over the last few years our lab at the University of California, San Francisco (UCSF) has used HTS to discover activators and inhibitors of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel.

In studies of the cystic fibrosis transmembrane conductance regulator membrane protein, Forman - Kay found disordered cytoplasmic elements that provide the flexibility needed to integrate various inputs to drive the opening and closing of a membrane channel.