Molecular mechanism underlying diseases (conformational diseases,
cystic kidney disorders, neuromuscular diseases, inflammation, iron - related diseases, disorders of human reproduction, osteoporosis and bone diseases) are being investigated by many groups with robust animal and cellular models and patients» biological samples.
Copper deficiency may occur in preterm infants, infants fed with cow's milk formula, chronic alcoholics, individuals with
cystic fibrosis, Crohn's or celiac disease or other small intestinal
disorder affecting absorption of copper, gastric bypass (bariatric surgery for weight loss)[3],
kidney patients on hemodialysis, those who take zinc supplements or a metal binder penicillamine and in individuals with hereditary
disorders of copper metabolism [1].