Appropriately diagnosed and treated complex gastrointestinal diseases including but not limited to esophageal dysmotility, gastroesophageal reflux, pancreatitis, pancreatic
cystic lesions, inflammatory bowel disease, irritable bowel syndrome, and colorectal diseases
«Studies are underway to interrogate the genomic signature of circulating pancreas cells from patients with precancerous
cystic lesions,» says Rhim.
They studied three groups of patients: those who were cancer - free, those diagnosed with precancerous
cystic lesions, and patients with pancreatic cancer.
«As scientists, we have tried to figure out which
cystic lesions are benign, which are pre-cancerous and which are malignant,» Dr. Yip - Schneider said.
First author Michele T. Yip - Schneider, Ph.D., associate research professor of surgery, and senior author C. Max Schmidt, M.D., Ph.D., MBA, professor of surgery, biochemistry and molecular biology, report this is the first cyst fluid protein biomarker that can differentiate serous cystic neoplasms, a benign type of
cystic lesion, from all other cancerous or precancerous cystic lesions without surgery.
The study included 149 patients who underwent an operation to remove a pancreatic
cystic lesion.
Not exact matches
Pancreatic Intraepithelial Neoplasia (PanIN) and mucinous
cystic neoplasm (MCN) also are
lesions that precede pancreatic cancer.
Dr. Kambadakone highlights the role of this new CT technology in detecting
lesions in the liver, assessing response to treatment for abnormalities such as adenoid
cystic carcinoma and potentially determining the degree of fibrosis in diffuse liver disease.
Severe forms of nodulo -
cystic acne which are resistant to therapy, particularly
cystic acne and acne conglobata, especially when the
lesions involve the trunk.
Some
lesions are multilobulated and
cystic.