Particular
cytidines in transcripts in chloroplasts and mitochondria of plant cells undergo modification to uridine by RNA editing (1).
Not exact matches
As these cells rapidly proliferate, they also express high levels of an enzyme known as activation - induced
cytidine deaminase (AID), which induces mutations
in their DNA.
In others, they changed pyrimidine RNA nucleotides, with
cytidine or uracil bases, into pyrimidine DNA nucleotides with
cytidine or thymidine bases.
The activation induced
cytidine deaminase (AID) efficiently targets DNA
in nucleosomes, but only during transcription.
Predominant role for activation - induced
cytidine deaminase
in generating IgG anti-nucleosomal antibodies of murine SLE.
Global demethylation requires activation - induced
cytidine deaminase (AID)- mediated downregulation of UHRF1 protein, and abolishing demethylation leaves thousands of hypermethylated regions
in the iPSC genome.