Sentences with phrase «cytochrome p»

ITRAFUNGOL is a cytochrome p - 450 inhibitor and may increase or prolong plasma concentrations of other drugs metabolized by this pathway.

Case reports of mania induction with St John's wort have resulted in limited use of this herbal for the treatment of both major depressive disorder and bipolar disorder.45, 46 Interactions between St John's wort and conventional drugs are mediated by the induction of cytochrome P - 450 3A4, which results in increased metabolism and decreased absorption of widely used drugs, including digoxin, anticoagulants, antiretrovirals, oral contraceptives, statins, and cyclosporine.47

Maines MD, Kappas A. Regulation of cytochrome P -450-dependent microsomal drug - metabolizing enzymes by nickel, cobalt, and iron.

The second phase (Phase II) of detoxification occurs in the cytochrome P - 450 enzyme system in the membranes of the endoplasmic reticulum, resulting in conjugation.

Not exact matches

Twelve percent encoded mitochondrial proteins such as succinate dehydrogenase complex, subunit B, iron sulfur (Ip)(τ statistic = — 0.76, P = 2.2 × 10 — 7), and ubiquinol — cytochrome c reductase subunit (τ statistic = — 0.65, P = 7.4 × 10 — 6)(Figure 1), and 6 % encoded lysosomal proteins (Supplemental Table 2, http://www.jci.org/cgi/content/full/112/12/1796/DC1).