Sentences with phrase «cytochrome b»

Phylogenetics and Molecular Divergence of Tilapia Fish (Oreochromis Species) Using Mitochondrial D - Loop and Cytochrome b Regions

Cytochrome b (1140 bp) only network (A) and d - loop (992 bp) only network (B) were generated from variable alignment sites.

Neither cytochrome b nor d - loop had enough variants to detect all island - specific lineages.

Independent analyses of two of the most widely used mtDNA genes in mammalian phylogeography, cytochrome b and D - loop, recovered only 15 and 20 haplotypes, respectively, instead of the 35 haplotypes recovered by sequencing whole mitogenomes (S2 Table).

Read Phylogenetic analysis of smelts (Osmeridae) based on the variation of cytochrome b gene, Russian Journal of Genetics on DeepDyve, the largest online fdating com review.

Atovaquone (ATO) is a safe and potent antimalarial drug that acts on cytochrome b (cyt.

Because the compound is metabolized too rapidly for study in mice, the team mimicked its effects by knocking out cytochrome B in C. albicans and infecting mice with this mutant strain.

Overall, the cytochrome B knock - out strain is much less virulent, and mice infected with it survive much longer than those with the wild - type strain.

This work led to Inz - 5, which exhibited dramatically improved potency and selectivity for fungal cytochrome B. Although cytochrome B is highly conserved across humans and many pathogenic fungi, including Cryptococcus neoformans, Aspergillus fumigatus, and Rhizopus oryzae, Inz - 5 exploits important differences in the amino acid sequence of the protein that enable selectivity for fungi.

Indeed, the researchers determined that Inz - 1 targets the cytochrome B protein required for mitochondrial production of ATP.

Because mitochondria are inherited from the mother, even breeding with parasites that don't have cytochrome b mutations won't help the parasite escape its fate.

This inverse relationship between mutation rate and body size also applied to the cytochrome b gene, part of the genome of the energy - processing mito - chondria.

The team looked at the DNA sequence of mitochondrial cytochrome b gene to gain more precise genetic information and gain insight into the history of the animals» migration routes.

Jon Wetton and his co-workers at the Forensic Science Service believe that amplifying fragments of the cytochrome b gene of the tiger's mitochondrial DNA may fill the bill.

They found 46 mutations in just one gene, the cytochrome b gene, in nine voles taken from the 30 - kilometre restricted zone around Chernobyl.

Malaria parasites can develop mutations in the cytochrome b gene that make them resistant to a drug called atovaquone, an ingredient in the antimalarial medication Malarone.

Not exact matches

Twelve percent encoded mitochondrial proteins such as succinate dehydrogenase complex, subunit B, iron sulfur (Ip)(τ statistic = — 0.76, P = 2.2 × 10 — 7), and ubiquinol — cytochrome c reductase subunit (τ statistic = — 0.65, P = 7.4 × 10 — 6)(Figure 1), and 6 % encoded lysosomal proteins (Supplemental Table 2, http://www.jci.org/cgi/content/full/112/12/1796/DC1).

Examples of adipose tissue transcripts whose expression correlated with body mass include (a) Csf1r and (b) CD68 antigen (Cd68), which correlated positively with body mass, (c) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)(Sdhb), and (d) ubiquinol — cytochrome c reductase subunit (Uqcr), which correlated negatively with body massb) CD68 antigen (Cd68), which correlated positively with body mass, (c) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)(Sdhb), and (d) ubiquinol — cytochrome c reductase subunit (Uqcr), which correlated negatively with body massB, iron sulfur (Ip)(Sdhb), and (d) ubiquinol — cytochrome c reductase subunit (Uqcr), which correlated negatively with body mass.

Certain particle compounds may directly generate ROS in vivo because of their surface chemistry (eg, metals, organic compounds, and semiquinones) or after bioactivation by cytochrome P450 systems (eg, polycyclic aromatic hydrocarbon conversion to quinones).6, 290 a, 290 b A particle surface or anions present on otherwise more inert particles may disrupt iron homeostasis in the lung and thereby also generate ROS via Fenton reactions.291 Other PM constituents may do so indirectly by the upregulation of endogenous cellular sources (eg, nicotinamide adenine dinucleotide phosphate [NADPH]-RRB- oxidase) 292,293 or by perturbing organelle function (eg, mitochondria) by taken - up PM components.261 Particle stimulation of irritant and afferent ANS fibers may also play a role in local and systemic oxidative stress formation.294 Given the rich antioxidant defenses in the lung fluid, secondarily generated oxidization products of endogenous molecules (eg, oxidized phospholipids, proteins) or a reduction in endogenous antioxidants per se may be responsible at least in part for the state of oxidative stress in the lungs (along with instigating the subsequent cellular responses) rather than ROS derived directly from PM and its constituents.