Sentences with phrase «cytogenetics as»

Not exact matches

Along with other clinical science departments, such as haematology, immunology, microbiology, molecular cytogenetics, histopathology, and medical physics, clinical biochemists carry out the diagnostic services that provide valuable information to doctors and other health care professionals within the National Health Service (NHS).

After a brief time as professor of Human Genetics, Medicine, and Pathology at the University of Chicago, he moved to the Laboratory Corporation of America (LabCorp) where he currently holds the position of strategic director of Cytogenetics and is one of the directors of LabCorp's cytogeneticsCytogenetics and is one of the directors of LabCorp's cytogeneticscytogenetics laboratory.

[5][6] In agreement with the International System for Human Cytogenetic Nomenclature (ISCN), this chromosomal translocation is designated as t (9; 22)(q34; q11).

A large variety of methods is used including genetic, molecular and cytogenetic techniques, fluorescence in situ hybridisation and DNA «combing», as well as high throughput sequencing approaches such as DNA - seq for mutation landscape analyses, RNA - seq for transcriptome analyses and ChIP - seq mapping of chromatin - associated proteins and their genome - wide modulation in response to DNA damages.

Low risk was defined as patients with the presence of inv (16) / t (16; 16) or t (8; 21) cytogenetic features, NPM1 or CEBPA mutations, or MRD < 0.1 % post-induction I in those with no high - risk features.

However, among patients who had uninformative cytogenetic or molecular features but who were MRD < 0.1 % at the end of induction I, the disease - free survival (HR, 1.86; 95 % CI, 1.18 — 2.92; P =.008) and overall survival (HR, 1.91; 95 % CI, 1.01 — 3.61; P =.046) were almost twice as high in patients who received five treatment courses compared with four courses.

The high resolution that is achieved by these techniques, particularly by microarray technologies such as array comparative genomic hybridization, is blurring the traditional distinction between cytogenetics and molecular biology.

Cytogenetic analysis now extends beyond the simple description of the chromosomal status of a genome and allows the study of fundamental biological questions, such as the nature of inherited syndromes, the genomic changes that are involved in tumorigenesis and the three - dimensional organization of the human genome.

She recently served as editor - in - chief of Cancer Genetics, and is a member of the International System for Cytogenetic Nomenclature committee.

However, being a complex multistep process, cancer cytogenetics are broadened to «cytogenomics,» with complementary resources on: general databases (nucleic acid and protein sequences databases; cartography browsers: GenBank, RefSeq, UCSC, Ensembl, UniProtKB, and Entrez Gene), cancer genomic portals associated with recent international integrated programs, such as TCGA or ICGC, other fusion genes databases, array CGH databases, copy number variation databases, and mutation databases.

He has been most involved in the defense of labs in Pap smear (cytology) and cytogenetics litigations, including litigating these matters as national counsel to the largest clinical laboratory in the country, in the state and federal courts of numerous states, including New York, New Jersey, Ohio, Illinois, Missouri, Texas, California, and Arizona.

Mr. Sidoti has represented the entire range of laboratory and other healthcare professionals and para-professionals, including pathologists, cytotechnologists, and lab technicians, on behalf of major clinical laboratories and smaller entities, in matters involving the disciplines of cytology, pathology, and cytogenetics, as well as general laboratory testing in the areas of chemistry, hematology, and toxicology.

The techniques of karyotyping such as culturing, harvesting, staining and chromosomal analysis need patience, accuracy and particular skills and I had proved to be an excellent and highly skilled cytogenetic technologist