The Human Functional Genomics Project, run by professors Mihai Netea and Leo Joosten at Radboud university medical center, UMCG Professor Cisca Wijmenga and Professor Ramnik Xavier at the Broad Institute of MIT and Harvard investigated how differences in
cytokine production during a Borrelia infection in 500 healthy volunteers can be explained.
Not exact matches
Dr. Wang plans to continue studying the effects of TNF and IL - 17 on melanocytes, and would like to expand the research to 3D skin models — fabricated samples of tissue in vitro that behave like human skin — that would give a better visual of how the melanin
production process is being disrupted by these two
cytokines during skin inflammation or wound healing.
In volunteers who received a BCG vaccination, she observed an increase in
cytokine production (proteins that control immune cells) and in the number of receptors that play a role
during the recognition of intruders.
During sleep, cortisol levels are low, allowing for increased activity of pro-inflammatory hormone and
cytokine production.
That basically means the compounds in Elder have the ability to raise and lower
cytokine production in your body so that your cells are better able to communicate
during an immune response.
It also tends to act in the body's
production of IL - 10 if it is taken
during infection, downregulating the levels of other
cytokines and necessary, but if taken early in the disease process, it inhibits viral upregulation of IL - 10 and increases antiviral
cytokine production and activity.»
Interestingly, evidence suggests that free radical and inflammatory
cytokine production slow down
during fasting and protective
cytokine production increases and protects the brain from oxidative damage.
We expected that higher levels of hostile marital behavior would be associated with slower healing of wounds, lower
production of proinflammatory
cytokines in blister chamber fluid, and higher
cytokine production in peripheral blood; however, short - term marital strife would magnify these relationships such that more hostile couples would show relatively greater deficits on these dimensions relative to low - hostile couples
during and following the conflict visit.
Thus, a series of studies have shown that marital conflict alters physiological functioning, and hostile behavior, particularly
during conflict, markedly enhances adverse physiological changes; moreover, women appear to be more adversely affected than men.5 In this study, we extended this line of research to assess how hostile marital behavior modulated an important health outcome, wound healing, as well as local and systemic proinflammatory
cytokine production.
Couples» interpersonal behavior, wound healing, and local and systemic changes in proinflammatory
cytokine production were assessed
during each research unit admission.