Sentences with phrase «cytokine secretion»
"Cytokine secretion" refers to the release of small proteins called cytokines by cells in our body. These cytokines act as messengers that help regulate our immune system and communicate important signals between cells. Full definition
We show that synNotch receptors can be used to sculpt custom response programs in primary T cells: they can drive a la carte cytokine secretion profiles, biased T cell differentiation, and local delivery of non-native therapeutic payloads, such as antibodies, in response to antigen.
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Initial studies demonstrated that ligation of 4 - 1BB on T cells could deliver costimulatory signals resulting in either increased proliferation or enhanced cytokine secretion and also control clonal expansion and differentiation of effector and memory T cells.
Senescent fibroblasts secreted oxidized HMGB1, which stimulated cytokine secretion through TLR - 4 signaling.
«Selenostasis», which is found to be compromised in Hashimoto's thyroiditis and Graves» disease, is critical to counterbalance iodine, because «Selenium enhances CD4 + / CD25 FOXP3 and T regulatory cells activity while suppressing cytokine secretion, thus preventing apoptosis of the follicular cells and providing protection from thyroiditis» (31, p. 721).
Diverse signaling pathways through the SDF - 1 / CXCR4 chemokine axis in prostate cancer cell lines leads to altered patterns of cytokine secretion and angiogenesis.
The degree of lymphocyte proliferation, regulatory T - cell generation and cytokine secretion were measured.
The lack of cysteine proteinase inhibitor stefin B influence inflammasome activation and cytokine secretion
The alpha2 beta1 integrin provides a co-stimulatory signal required for mast cell activation, cytokine secretion and initiation of innate immunity.
This includes research on both the innate and adaptive immune response and processes such as pathogen recognition, immune cell activation and recruitment, cytokine secretion, inflammation, and antibody production.
The cell culture supernatant was collected and cytokine secretion was determined using the Mouse IFN - gamma Quantikine ® ELISA Kit (Catalog # MIF00), the Mouse IL - 4 Quantikine ® ELISA Kit (Catalog # M4000B), and the Mouse IL - 17 Quantikine ® ELISA Kit (Catalog # M1700).
T lymphocytes can recognize these new or altered antigens and are able to fight tumour through direct cytotoxicity or cytokine secretion.