Sentences with word «cytolytic»

If you're suffering from the symptoms of a yeast infection but the vaginal swab comes back negative, you should suspect cytolytic vaginosis.

In our study, we demonstrated that VPA administration in tumor models maintained cytolytic activity of donor T cells while inhibiting the proinflammatory function of Th1 and Th17 cells and, thereby, separated GVHD and the GVL effect.

T11 / CD2 activation of cloned human natural killer cells results in increased conjugate formation and exocytosis of cytolytic granules.

These fCD8 + cells have cytolytic potential and can be redirected to target and kill HIV - infected cells using bispecific antibodies.

Analysis of antigens recognized on human melanoma cells by A2 - restricted cytolytic T lymphocytes (CTL).

In this model, FHL is triggered by the lymphocytic choriomeningitis virus (LCMV), a virus that would normally be cleared by the CD8 T cell cytolytic response in perforin - sufficient mice.

In addition, the CD8 subset primarily function as cytolytic killers for clearing pathogen - infected cells or for targeting tumors.

Familial hemophagocytic lymphohistiocytosis type 2 (FHL2) is a classic genetic form of hemophagocytic lymphohistiocytosis (HLH) caused by mutations within the perforin gene that limit cytolytic elimination of viral infections by CD8 T cells and NK cells (1).

We report here that, despite their phenotypic and cytolytic similarities, Ly49 + CD8 + T cells and conventional Ly49 - CD44high memory - phenotype CD8 + T cells present strikingly distinct features.

In addition, we observed that donor T cells recovered from VPA - treated BMT recipients and controls on day 14 showed comparable cytolytic activity against host - type leukemia cells (Fig. 5F).

These results indicate that Ly49 expression is associated with a differentiation program of cytolytic CD8 + T cells triggered upon chronic antigenic exposure.

Profound Metabolic, Functional and Cytolytic Differences Characterize HIV - Specific CD8 T Cells in Primary and Chronic HIV Infection.

The TCGA analysis showed tumors with PTEN loss in the background of BRCA1 / 2 deficiency had lower levels of cytolytic immune molecules and immune - activating pathways that would normally drive immune responses against tumors.

A yeast infection (candidiasis) is fungal overgrowth, but cytolytic vaginosis is bacterial overgrowth.

Stress decreases lymphocyte cytolytic activity in the young monkey even after blockade of steroid and opiate hormone receptors

Effect of CD4 + CD25 + and CD4 + CD25 - T regulatory cells on the generation of cytolytic T cell response to a self but human tumor - associated epitope in vitro.

Improved proliferation of antigen - specific cytolytic T lymphocytes using a multimodal nanovaccine.

A team of international researchers headed by scientists from the University of Tübingen has deciphered the workings of a cytolytic toxin, which is produced by some of the world's most devastating crop diseases.

He showed that engagement of PD - 1 by PD - L1 or PD - L2 inhibited T cell activation, cytokine production, and cytolytic activity whereas blockade enhanced these activities.

Neither a yeast infection nor cytolytic vaginosis are sexually transmitted, meaning you don't typically «catch» them from your partner, however sex can lead to imbalance in the vaginal and penile flora so both partners (same sex or opposite sex) can develop similar symptoms.

Only a yeast infection will present with a positive swab for candida, if you have cytolytic vaginosis the candida swab will be negative.

In these cases the yeast infection you think you have may actually be cytolytic vaginosis.

It sounds scary, cytolytic vaginosis, but it really isn't.

Alpha Herpesviruses such as FHV - 1 cause disease by two distinctly different mechanisms: 1) cytolytic (cell - rupturing) disease which involves active viral replication and destroys the epithelial cells of the cornea and conjunctiva causing ulceration; and, 2) immune - mediated disease results from the deposition of viral antigen in subepithelial tissues.

Allergic (hypersensitivity) and immune - mediated reactions: Type 1 (acute anaphylaxis): angiodema (especially the head), anaphylaxis (shock) and death; Type 2 (cytolytic): immune - mediated hemolytic anemia, immune - mediated thrombocytopenia (suspected only; causality has not been confirmed); Type 3 (immune - complex): cutaneous ischemic vasculopathy associated with rabies vaccine, corneal edema («blue - eye») associated with CAV - 1 vaccine, immune - mediated disease.