Sentences with phrase «cytolytic immune»
The TCGA analysis showed tumors with PTEN loss in the background of BRCA1 / 2 deficiency had lower levels of cytolytic immune molecules and immune - activating pathways that would normally drive immune responses against tumors.
https://www.pennmedicine.org/ Not exact matches
Cutting edge: differential segregation of the SRC homology 2 - containing protein tyrosine phosphatase - 1 within the early NK cell immune synapse distinguishes noncytolytic from cytolytic interactions.
Visualization of signaling pathways and cortical cytoskeleton in cytolytic and noncytolytic natural killer cell immune synapses.
Alpha Herpesviruses such as FHV - 1 cause disease by two distinctly different mechanisms: 1) cytolytic (cell - rupturing) disease which involves active viral replication and destroys the epithelial cells of the cornea and conjunctiva causing ulceration; and, 2) immune - mediated disease results from the deposition of viral antigen in subepithelial tissues.
Allergic (hypersensitivity) and immune - mediated reactions: Type 1 (acute anaphylaxis): angiodema (especially the head), anaphylaxis (shock) and death; Type 2 (cytolytic): immune - mediated hemolytic anemia, immune - mediated thrombocytopenia (suspected only; causality has not been confirmed); Type 3 (immune - complex): cutaneous ischemic vasculopathy associated with rabies vaccine, corneal edema («blue - eye») associated with CAV - 1 vaccine, immune - mediated disease.