Not exact matches
It is far more likely, however, that the egg - cell
cytoplasm with its stripping factor will
reprogram all the genetic material including the alterations made in the donor nucleus that were intended to prevent the creation of the zygote.
The second biological objection is that «the egg - cell
cytoplasm» will «
reprogram all the genetic material including the alterations made in the donor nucleus that were intended to prevent the creation of the zygote.»
This hypothesis underestimates the opposing power of the egg cell
cytoplasm to
reprogram the genes in the donor - cell nucleus.
«By gaining direct access to the
cytoplasm of the cell we have achieved genetic
reprogramming at an incredible high efficiency.
The researchers believe the experiment worked because the zygotes were paused at a stage in which the nucleus has dissolved and the molecules responsible for
reprogramming are mixed throughout the
cytoplasm where they can affect the injected DNA.
Oocytes, unfertilized eggs, have an exceptionally large
cytoplasm containing RNA and protein that drives the early cleavage divisions and
reprograms the male pronucleus to support early development.