Not exact matches
Cytoplasmic tail of gp41 The structures of three membrane - associated cytoplasmic tails of gp41 are shown in red and orange, from this illustration of the trimeric spike
Cytoplasmic tail of gp41 The
structures of three membrane - associated
cytoplasmic tails of gp41 are shown in red and orange, from this illustration of the trimeric spike
cytoplasmic tails of gp41 are shown in red and orange, from this illustration of the trimeric spike
structure.
They found that the N - terminal end of the
cytoplasmic tail of gp41, measuring 45 amino acid residues, lacked a regular secondary
structure and was not associated with the membrane, which wraps around an HIV - 1 viral particle like the leather cover of a baseball.
Saad says the
structure opens up whole new areas of research: How the
cytoplasmic tail stabilizes the envelope protein
structure, how it affects membrane mobility of the envelope protein
structure, and how it helps coordinate membrane - binding and the association of 2,000 HIV - 1 Gag polyproteins underneath the membrane surface.
Knowledge of this
structure, called the
cytoplasmic tail of gp41 protein, will help researchers further understand how the virus infects human cells and how progeny viruses are assembled and released from infected cells.