The gene discovered in the research couples the exocytosis - regulating protein Sec10 with formin, a protein that regulates the remodeling of the actin
cytoskeleton critical to forming cell shapes.
Not exact matches
Microtubules are a
critical component of the
cytoskeleton, vital for cell division and, because of that, an excellent target for chemotherapy drugs.
4.1 R is
critical for the organisation and maintenance of the spectrin - sctin
cytoskeleton in erythrocytes, via intereactions with intregral membrane proteins.
Specifically, the team hypothesizes that microRNA miR - 24 is a key regulator of actin
cytoskeleton dynamics (i.e. the inner structural support of a cell); therefore, it plays a
critical role in regulating multiple disease processes, including the angiogenesis (blood vessel growth), inflammation, and fibrosis (thickening and scarring of tissue) associated with choroidal neovascularization (CNV) in wet AMD.