Not exact matches
The actin
cytoskeleton of both
cells is exposed; the white blood
cell nucleus is shown in brown and the large actin - rich extension that dismantles the
endothelial actin is shown in yellow.
Dismantling structural filaments within the
cytoskeletons — the internal skeletons —
of the
endothelial cells creates the large holes, which can be several microns in diameter.
Cytoadhesion
of P. falciparum in the brain leads to a large number
of deaths each year and is a consequence
of exported parasite proteins, some
of which modify the erythrocyte
cytoskeleton while others such as PfEMP1 project onto the erythrocyte surface where they bind to
endothelial cells.