Sentences with phrase «cytotoxic activity»
"Cytotoxic activity" refers to the destructive ability of certain substances or cells to kill or damage cells in the body. It is often associated with the immune system's response to eliminate harmful cells, such as cancer cells or infected cells, by attacking and destroying them. Full definition
Natural Killer (NK) cells, lymphocytes of the innate immune system with strong cytotoxic activity, play a major role in the immune response against tumors.
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Here we show that MAIT cells display cytotoxic activity towards MR1 overexpressing non-hematopoietic cells cocultured with bacteria.
Noto A, Ngauv P, Trautmann L. Cell - based Flow Cytometry Assay to Measure Cytotoxic Activity.
We developed a series of novel proteasome inhibitors selective for each of the three protease sites and demonstrated the relative importance of inhibiting each site for cytotoxic activity (Shabaneh et al, PlosOne 2013).
An antibacterial and anti-fungal compound that also has cytotoxic activity against skin cells.
In fact at the doses used, the chemotherapy is not having direct cytotoxic activity, i.e. not directly killing the cancer cells.
Flavopiridol inhibits several cellular kinases and has demonstrated cytostatic and cytotoxic activity in vitro and in vivo in numerous human tumor cell lines and xenograft models (including human breast, prostate, and lung carcinoma) at clinically achievable concentrations.
Naïve T cells then expand and differentiate into effector T lymphocytes that acquire either cytotoxic activity or secrete high amounts of certain cytokines.
iTeos has patented selective proprietary A ₂ ₐ antagonists which inhibit adenosine - mediated suppression of T - cell activation and cytotoxic activity and promoted anti-tumor efficacy in mouse tumor models.