Sentences with phrase «cytotoxic compounds»
"Cytotoxic compounds" refers to substances that are toxic or harmful to cells. These compounds have the ability to damage or kill cells in the body. Full definition
Here we describe the development and preclinical characterization of a CD123 - targeting antibody - drug conjugate (ADC), IMGN632, that comprises a novel humanized anti-CD123 antibody G4723A linked to a recently reported DNA mono - alkylating payload of the indolinobenzodiazepine pseudodimer (IGN) class of cytotoxic compounds.
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The Arf6 pathway may also boost the drug resistance of breast cancer cells, and Hashimoto et al. found that inhibiting Rab11b, or a component of the Arf6 pathway called EPB41L5, increased the sensitivity of MDA - MB - 231 cells to two different cytotoxic compounds.
The plant world holds the keys to many natural anti-inflammatory compounds, grounding compounds, and even cell - selective cytotoxic compounds that kill cancer cells but not healthy cells.
Black Walnut is a type of walnut that contains large amounts of a cytotoxic compound called juglone.