All extracts were found to have
cytotoxic effects on the cancer cells, with the clove essential oil producing the highest cytotoxic effect.
(26) These studies also show that cadmium reduces insulin levels and has direct
cytotoxic effects on the pancreas.
Curcumin's anticancer effect is attributed to its ability to induce apoptosis in cancer cells without
cytotoxic effects on healthy cells.
Therefore, to overcome chemoresistance mediated by EMT, drug screening efforts have focused on eliminating the mesenchymal subpopulation by searching for drugs with preferential
cytotoxic effects on mesenchymal, rather than epithelial HMLE subpopulations [7].
In all these in vitro assays, kahweol treatments were carried out under conditions (kahweol concentration and duration of treatment) that did produce
no cytotoxic effect on cells.
Although no studies have directly confirmed its effect on breast cancer stem cells thus far, the outlook is positive that one day the connection may be made considering
its cytotoxic effect on breast cancer cells, in general, has already proven to be so high.
And radiation therapy causes what's called
a cytotoxic effect on those.
Not exact matches
The researchers demonstrate that the use of specific
cytotoxic substances can also have a beneficial
effect on the body's immune system.
Thus, the molecule's observed «
effect»
on cell growth is nothing more than the well - known
cytotoxic effect of alcohol.
Cytotoxic effects of bilberry extract
on MCF7 - GFP - tubulin breast cancer cells.
Furthermore, they may be
cytotoxic or may instead exert an anticancer
effect by acting
on one or more aspects of the tumor microenvironment either alone or in combination with existing anticancer treatments [3, 4].
SENS Foundation is funding ongoing work in the lab of Dr. Janko Nikolich - Zugich to investigate the
effects of clearance of anergic, «senescent»
cytotoxic CD8 + T - cells
on immunosenescence, (22) and is interested in the targeting of other such cells.
Importantly, this automated screening assay allowed us to interrogate some of the specific molecular mechanisms that may be responsible for the targeted
cytotoxic effect amiodarone HCL had
on NSCs and not cells differentiated from NSCs.
One study examined the
cytotoxic effects of different types of clove extract
on breast cancer cell lines, including water - based, alcohol - based and essential oil extracts.