Sentences with phrase «cytotoxicity against»

In addition, it demonstrates a significant antihyperglycemic effect and cytotoxicity against prostate cancer.

Dsg3 CAAR - T cells exhibit specific cytotoxicity against cells expressing anti-Dsg3 BCRs in vitro and expand, persist, and specifically eliminate Dsg3 - specific B cells in vivo.

Some compounds of the dozens of variations the scientists created exhibit potent cytotoxicities against certain cancer cells, including a drug - resistant cell line, Nicolaou said.

Not exact matches

The cytotoxicity of niclosamide and oxyclozanide were evaluated against HepG2 human liver carcinoma cells and both drugs caused a dose - dependent loss in cell viability [35,36].

The mechanism of action is based on the activation of macrophages to defend against tumors by direct tumor cytotoxicity and consequently they secrete cytokines which recruit secondary immune cells, presenting antigen to T cells [5 - 7].

A new study demonstrates that it is possible to vaccinate patients with MDS against a decitabine - induced antigen and that the level of induced expression is sufficient to trigger cytotoxicity in patient - derived vaccine - induced T cells.

Furthermore, the levels of transcripts of two AlkB genes that protect against the cytotoxicity of methylating agents through repair of the specific DNA lesions generated in single - stranded DNA, Alkhb3 (alkylation repair homolog 3) and Alkhb8 (alkylation repair homolog 8), was lower in the IVC males.

Moreover, gladiolin displayed low mammalian cytotoxicity and good activity against several M. tuberculosis clinical isolates, including four that are resistant to isoniazid and one that is resistant to both isoniazid and rifampicin.

Selenium helps protect against iodine toxicity by ensuring that glutathione peroxidase activity in the thyroid is adequate to avoid cytotoxicity of hydrogen peroxide (34).