Sentences with phrase «dacarbazine in»
The MEK inhibitor binimetinib resulted in improved progression - free survival and response rates vs dacarbazine in patients with NRAS - mutated metastatic melanoma.
http://www.cancernetwork.com/ Not exact matches
In the control arm, dacarbazine was not used in compliance with the approval, however: Instead of administration in combination with another drug (doxorubicin), dacarbazine was used as monotherapy, and a different dosage was used in the beginning of the treatmenIn the control arm, dacarbazine was not used in compliance with the approval, however: Instead of administration in combination with another drug (doxorubicin), dacarbazine was used as monotherapy, and a different dosage was used in the beginning of the treatmenin compliance with the approval, however: Instead of administration in combination with another drug (doxorubicin), dacarbazine was used as monotherapy, and a different dosage was used in the beginning of the treatmenin combination with another drug (doxorubicin), dacarbazine was used as monotherapy, and a different dosage was used in the beginning of the treatmenin the beginning of the treatment.
In its dossier, the drug manufacturer used one study of direct comparison that tested eribulin against dacarbazine.
Plerixafor in combination with the chemotherapeutic agent dacarbazine significantly suppressed the metastatic phenotype of melanoma compared to dacarbazine alone [40].
Dacarbazine - based chemotherapy as first - line treatment in noncutaneous metastatic melanoma: multicenter, retrospective analysis in Asia.
[61,62] Small retrospective studies of biochemotherapy (cisplatin, vinblastine, dacarbazine, interferon alfa - 2b, and IL - 2) also demonstrated activity that was similar in cutaneous and mucosal melanomas.
Although dacarbazine has been part of the standard of care for metastatic melanoma for more than 30 years, it has never been shown to increase overall survival in this patient population.
Mature results of a phase III randomized trial of bacillus Calmette - Guerin (BCG) versus observation and BCG plus dacarbazine versus BCG in the adjuvant therapy of American Joint Committee on Cancer stage I - III melanoma (E1673).