Sentences with phrase «damage during cell division»
Repairing the chromosome damage during cell division caused it to be defective.
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A diffusion barrier regulates the sorting of damaged proteins during cell division.
The de-repressed satellite RNAs induced damage to the chromosomes by fusing them inappropriately and breaking them in what is called genomic instability, a catastrophic event for the cell during cell division, which can lead to cancer.
Moreover, somatic mutation burden increases during a lifetime as a result of accumulating errors occurring either during cell division or because of environment - induced DNA damage.
p53 not only down regulates cell division during the normal process of aging and senescence, but it is also involved in a response to DNA damage [27,28] and telomere shortening [29].