Sentences with phrase «damage models in»

I've spoken about great damage models in other racing games, but it wasn't until I saw the engine bay of my Ford GT shake about at speeds after a crash that I realised just how perfect it is in Most Wanted.

Padding the game with unfinished content and obsessing over modeling the visuals of the rest of them to the point of ignoring innovations in other very important areas (like the above mentioned accurate modeling of bumps on the tracks, etc) that affect gameplay and aren't just pretty... even the damage modeling in GT was lazily thrown together when it was introduced in GT5.

It's difficult to get a feel for the handling and the damage modelling in this pre-alpha state, but everything runs the way you'd expect, though the option of remapping some of the keys would be nice.

Not exact matches

COO Sheryl Sandberg said in an interview with CNBC on Thursday that the company doesn't look at matters of user privacy in terms of long - term damage to stock price or its business model.

The improvements to water resistance in the iPhone 7 and 7 Plus, compared with earlier iPhone models, make the open - face design of the TuneBand less worrisome than before — if you run in the rain, you don't need to worry about moisture damaging your phone.

Speaking in Germany, Amazon CEO Jeff Bezos said his company had a duty to educate regulators but would work with any new constraints — even if they damage its business model.

Losses are impossible to avoid in this business, but our market timing model typically enables us to step aside with very little damage done to the bottom line, and that is fine with us.

While many people will point to Hurricane Katrina and the 2005 damage done in New Orleans and along the Gulf Coast as a model for what we may expect from Harvey, the 2016 floods in Baton Rouge may be more realistic.

If Krugman's criticism of the «mythology» is correct, the Canadian banking system of that era should have been a basket case, but instead it was a model for the world precisely because it lacked the two most damaging government regulations present in the US.

Its X-ray models can detect a variety of contaminants including metal, glass, bones, shells, stones, hard rubber and plastic down to 0.3 mm in size, and can also be used for other quality control operations such as product grading by length, presence of clips, voids in product, product deformation, missing or damaged pieces, and fill - level control.

Modeling ADHD - type arousal with unilateral frontal cortex damage in rats and beneficial effects of play therapy.

Modeling ADHD - type arousal with unilateral frontal cortex damage in rats and beneficial effects of play therapy, Brain and Cognition.

In some sense, Facebook's steady extension of the pay - to - play model is analogous to a natural disasters: you can't completely avoid either, but you CAN act preemptively to mitigate the worst of the damage.

These are all nations with legislature modelled closely on Westminster — clearly the mother of parliaments has been surpassed in maturity by her children, who know they can choose a partisan Speaker without fear that it will damage parliamentary democracy.

Any new barriers, particularly customs ones, damage the «just - in - time» model our auto manufacturers, and many other industries, rely on.

In an animal model, this technique successfully repaired nerve damage over distances of up to 6 cm: the nerve fibres grew back together in a functional way within 9 monthIn an animal model, this technique successfully repaired nerve damage over distances of up to 6 cm: the nerve fibres grew back together in a functional way within 9 monthin a functional way within 9 months.

Under this model (described in the paper, which was submitted to arXiv.org), during the next 50 years the potential for economic damage will depend primarily on the rising odds of a strong solar storm over time.

«The successful restoration of normal function demonstrated in the mouse models suggests that if we can develop therapies to address the loss of Mecp2,» Baylor's Zoghbi says, «we may be able to reverse neurological damage in children and adults with Rett, autism and related neuropsychiatric disorders.»

By including the whole world, Stein says, the model should enable scientists to test forecasts of big, damaging earthquakes in a practical amount of time.

Another system in development, called MANTIS - K, will feed the OEF's forecasts into models of local vulnerability to forecast deaths, injuries and damage.

In the present study, the researchers have discovered a reason for reduced fertility in people with autoimmune polyendocrine syndrome type 1 (APS1), which increases the risk of developing autoimmune disease (caused by the immune system attacking and damaging healthy cells) and which is often used as a model for autoimmune disease in generaIn the present study, the researchers have discovered a reason for reduced fertility in people with autoimmune polyendocrine syndrome type 1 (APS1), which increases the risk of developing autoimmune disease (caused by the immune system attacking and damaging healthy cells) and which is often used as a model for autoimmune disease in generain people with autoimmune polyendocrine syndrome type 1 (APS1), which increases the risk of developing autoimmune disease (caused by the immune system attacking and damaging healthy cells) and which is often used as a model for autoimmune disease in generain general.

The researchers found that the immune cells in the skin of this animal model generated large amounts of the cytokine IL - 17 — a protein of the immune system that activates cellular inflammation in response to damage.

The team also used a separate computer model developed by the Federal Emergency Management Agency to estimate the costs: more than $ 250 million in building and crop damage in the flooded area.

«Moving to non-invasive and repeatable methods of nerve fiber measurements such as in vivo corneal confocal microscopy would enhance study of peripheral neuropathy by enabling early detection of damage, progression of nerve fiber deterioration, and enable assessment of therapeutic strategies in the SIV / macaque model,» explains Dr. Mankowski.

In a study published in the Journal of Neuroscience, researchers from Case Western Reserve University School of Medicine showed certain immune cells — neutrophils — can clean up nerve debris, while previous models have attributed nerve cell damage control to other cells entirelIn a study published in the Journal of Neuroscience, researchers from Case Western Reserve University School of Medicine showed certain immune cells — neutrophils — can clean up nerve debris, while previous models have attributed nerve cell damage control to other cells entirelin the Journal of Neuroscience, researchers from Case Western Reserve University School of Medicine showed certain immune cells — neutrophils — can clean up nerve debris, while previous models have attributed nerve cell damage control to other cells entirely.

Specifically, the Mount Sinai study was designed to test whether pharmacological compounds designed to block the function of XPO1 / CRM1 could stop disease progression in mouse models that exhibit some of the characteristics of MS. Researchers found that two chemical agents (called KPT - 276 and KPT - 350) prevented XPO1 / CRM1 from shuttling cargo out of the nucleus of nerve cells, which protected them from free radicals and structural damage.

Left: Illustration of the number of defects in materials predicted by the old «Kinchin - Pease» equation; Right: Illustration of the actual number of remaining damage, consistent with the prediction of the new model.

Mochly - Rosen and colleagues identified several other potential biomarkers that were elevated in HD model mice, including the levels of 8 - hydroxy - deoxy - guanosine, a product of oxidative DNA damage, in the urine and the presence of mutant huntingtin aggregates and oxidative damage in muscle and skin cells.

A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in mouse models of multiple sclerosis, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nature Neuroscience.

In their article «Improving atomic displacement and replacement calculations with physically realistic damage models» published in Nature Communications, the scientists present the outcome of a reconsideration of the issuIn their article «Improving atomic displacement and replacement calculations with physically realistic damage models» published in Nature Communications, the scientists present the outcome of a reconsideration of the issuin Nature Communications, the scientists present the outcome of a reconsideration of the issue.

«Transplanted hematopoietic stem cells reverse damage caused by neuro - muscular disorder: In mouse model of Friedreich's ataxia, a single infusion measurably restored normal cellular functions.»

«The compounds identified in this study, when administered orally, both reduced the inflammation that is a hallmark of multiple sclerosis and protected against the nerve cell damage seen in mouse models of the disease,» said Jeffery Haines, PhD, a post-doctoral fellow at Mount Sinai and the study's lead author.

This individualized therapy would strategically place «firebreaks» of much smaller burns around areas from which the model predicts that vascular damage will spread in that patient, greatly reducing the total amount of damage and reducing the probability that damage will spread between the burns and propagate despite treatment.

«Drought in these models is treated as a light switch» — either on or off — «but in the real world we know that drought damages trees, and it can take a while for trees to repair this damage and recover.»

Working with a mouse - model of parainfluenza virus infection, Sendai virus, which causes similar symptoms and patterns of tissue damage to RSV, researchers found that mice fared much worse in fighting the infection when their cells lacked IL - 27 signaling.

To mitigate the impact of future smoke events, the team developed a model framework which could help governments and policymakers in Southeast Asia identify, in almost real time, the fires with the highest potential to cause damage to human health.

Now, the researchers have discovered an alternative in a mouse model: in the case of breast tumours with a specific defect in DNA repair, the animals can be cured using already established, cheap chemotherapy drugs, if enough DNA damage can be inflicted on the resting tumour cells.

The researchers, who evaluated the BSCB in test animals at seven and 30 days after stroke modeling, found that ischemic stroke damaged the gray and white matter in the cervical spinal cord on both sides of the spinal column, based on analysis of electron microscope images.

A team of researchers at the University of South Florida investigating the short and long - term effects of ischemic stroke in a rodent model has found that stroke can cause long - term damage to the blood - spinal cord barrier (BSCB), creating a «toxic environment» in the spinal cord that might leave stroke survivors susceptible to motor dysfunction and disease pathology.

«This study, carried out using laboratory rats modeling stroke, demonstrated that ischemic stroke — in both its subacute and chronic stages — damages the BSCB in a variety of ways, creating a toxic environment in the spinal cord that can lead to further disability and exacerbate disease pathology,» said study lead author Dr. Svitlana Garbuzova - Davis, associate professor in USF's Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair.

With this new understanding of how Del - 1 can inhibit periodontal bone loss — both by reducing inflammation and by restraining the activity of osteoclasts that resorb bone tissue — the researchers tested it, in a preclinical model of periodontitis observing that Del - 1 significantly reduced inflammation and tissue damage and that there was significantly less bone loss.

Studies in the mouse model further suggest that controlled expression of Lin28 can promote kidney development and therefore may hold clues to regeneration of damaged kidneys in adults.

In a bid to progress beyond the shotgun approach to fighting cancer — blasting malignant cells with toxic chemicals or radiation, which kills surrounding healthy cells in the process — researchers at the Harvard - MIT Division of Health Sciences and Technology (HST) are using nanotechnology to develop seek - and - destroy models to zero in on and dismantle tumors without damaging nearby normal tissuIn a bid to progress beyond the shotgun approach to fighting cancer — blasting malignant cells with toxic chemicals or radiation, which kills surrounding healthy cells in the process — researchers at the Harvard - MIT Division of Health Sciences and Technology (HST) are using nanotechnology to develop seek - and - destroy models to zero in on and dismantle tumors without damaging nearby normal tissuin the process — researchers at the Harvard - MIT Division of Health Sciences and Technology (HST) are using nanotechnology to develop seek - and - destroy models to zero in on and dismantle tumors without damaging nearby normal tissuin on and dismantle tumors without damaging nearby normal tissue.

Using an in vitro human blood brain barrier model, the researchers demonstrated that radiolabeled mAb2556 could cross the blood brain barrier and kill HIV - infected cells without any overt damage to the barrier itself.

But in studies of mouse models of the disease, cyclodextrins, even when administered peripherally, have significantly impacted the neurological damage; it's not known how.

This group's achievement shows the possibility to clarify the mechanism of human tumor formation, especially the molecular mechanism responsible for in the initial stage of cell cancerization due to DNA damaged by radiation in the initial stage, by using the model of budding yeast, a primitive eukaryote.

Scientists often compare the damage an incoming asteroid might do to that of a nuclear weapons test of equivalent energy, but Chelyabinsk proves that this model doesn't work in all cases.

None suffered any damage, and some carried sampling instruments that found no ash in places where models predicted it, sparking strong complaints from the airline trade body IATA.

The proposed model is highly - flexible - allowing for inclusion of damage information, such as information coming from the Humanitarian OpenStreetMap team, in the analyses.

A release of 50 billion tonnes of methane would bring forward by 15 to 35 years the date at which global temperature rise exceeds 2 ˚C above pre-industrial levels, the model shows, with most of the damage in the poorer parts of Africa, Asia and South America.