Sentences with phrase «damage neurons in»

Glucocorticoids can damage neurons in the hippocampi of rodents and primates.

In 2002 ethnobotanist Paul Cox from the Institute for Ethnobotany at the National Tropical Botanical Garden in Kalaheo, Hawaii, and neurologist Oliver Sacks from the Albert Einstein College of Medicine in New York City introduced a shocking theory about how Chamorros might be ingesting enough BMAA to damage neurons in the brain and spinal cord.

Geula and colleagues plan to investigate how the internal amyloid damages the neurons in future research.

Subramaniam and his colleagues also found lesions and damaged neurons in the cerebellum, confirming Rhes is sufficient to promote toxicity and showing that even those regions of the brain normally impervious to damage can become vulnerable if Rhes is overexpressed.

Although glial activation may have short - term benefits, there is consensus that in the long - term, these cells may contribute to the pathology of damaged neurons in glaucoma.

Not exact matches

We know from cases of brain damage and the effects of psychoactive drugs, that our experiences are caused by physical chemistry acting on our physical neurons in our brains.

Transplanted neurons controlled by light can drive muscle function in damaged mouse sciatic nerves.

They discovered that the chemicals and radiation used to kill tumor cells damage the stem cell reservoir in the hippocampus and nearly halt the formation of new neurons in both children and adults.

Hoxb8 is usually active in microglia, immune - system cells that clean up damaged neurons and attack pathogens in the brain.

In Nick's case, the cause was probably catastrophic damage to his olfactory receptor neurons.

ALD, for instance, is caused by mutations in a gene called ABCD1, leading to unusually high levels of a type of fatty acid that damages the material insulating some neurons.

The researchers caution, however, that it's not yet clear how closely the toxin - induced neural damage in rats mimics the state of diseased neurons in Parkinson's, especially because the mechanism that leads to such damage in humans remains unknown.

As well as offering a way to create souped - up organisms, changing neural connectivity could one day allow us to treat brain damage in people by rerouting signals around damaged neurons.

They then induced Parkinson's symptoms in laboratory rats by killing the rodents» dopamine - producing neurons with toxins, and injected the viruses into the damaged tissue of some of the animals.

In Alzheimer's disease, plaques of amyloid beta protein accumulate in the brain, damaging connections between neuronIn Alzheimer's disease, plaques of amyloid beta protein accumulate in the brain, damaging connections between neuronin the brain, damaging connections between neurons.

A major challenge in repairing the brain is obtaining cortical neurons from the appropriate layer and area in order to restore the damaged cortical pathways in a specific manner.

Their findings, reported June 17 in the journal Neuron, could lead to treatments for chronic pain conditions caused by nerve damage, such as diabetic peripheral neuropathy (DPN) and post-herpetic neuralgia (PHN), as well as chronic inflammation, like rheumatoid arthritis.

The results obtained by Afsaneh Gaillard's team and that Pierre Vanderhaeghen at the Institute of Interdisciplinary Research in Human and Molecular Biology show, for the first time, using mice, that pluripotent stem cells differentiated into cortical neurons make it possible to reestablish damaged adult cortical circuits, both neuroanatomically and functionally.

These stroke - related alterations in the cervical spinal cord indicate pervasive and long - lasting BSCB damage that would severely affect spinal cord function, wrote the researchers, adding that the widespread microvascular impairment in the gray and white matter of the cervical spinal cord aggravated motor neuron deterioration and had the potential to cause motor dysfunction.

The researchers found that mutant mice lacking Del - 1 had more severe attacks of the EAE than normal mice, with more damage to myelin, the fatty sheath that coats neurons and helps in the transmission of signals along the cell.

Using computer simulations, the authors succeeded in reconstructing the reorganization of the neurons in a way that conforms to experimental results from the visual cortex of mice and monkeys with damaged retinas.

«What we found is that, because of the lack of immune response (to the mesh electronics), which basically insulates neurons, we can deliver stimulation in a much more subtle way, using lower voltages that don't damage tissue.»

As study director Brack - Werner explained: «Several viral proteins are toxic to neurons and may cause immune damage in the brain.

In the study, scientists examined basal forebrain cholinergic neurons to try to understand why they are damaged early and are among the first to die in normal aging and in Alzheimer'In the study, scientists examined basal forebrain cholinergic neurons to try to understand why they are damaged early and are among the first to die in normal aging and in Alzheimer'in normal aging and in Alzheimer'in Alzheimer's.

It is made in abundance in the brain, especially in regions where damage to dopamine - producing neurons is known to give rise to Parkinson's.

In a study led by Duke Health and published in the journal Alcoholism: Clinical and Experimental Research, scientists demonstrate in rats that a short duration of the drug donepezil can reverse both structural and genetic damage that bouts of alcohol use causes in neurons, or nerve cells, in the young braiIn a study led by Duke Health and published in the journal Alcoholism: Clinical and Experimental Research, scientists demonstrate in rats that a short duration of the drug donepezil can reverse both structural and genetic damage that bouts of alcohol use causes in neurons, or nerve cells, in the young braiin the journal Alcoholism: Clinical and Experimental Research, scientists demonstrate in rats that a short duration of the drug donepezil can reverse both structural and genetic damage that bouts of alcohol use causes in neurons, or nerve cells, in the young braiin rats that a short duration of the drug donepezil can reverse both structural and genetic damage that bouts of alcohol use causes in neurons, or nerve cells, in the young braiin neurons, or nerve cells, in the young braiin the young brain.

These fatty acids may normally help dampen inflammation in the brain and protect neurons from damage, and lower levels in the brain have been implicated in several mental illnesses.

Oligodendrocyte death, occurring after a spinal cord injury, activates a process called de-myelination that results first in damage to surviving neuronal connections and finally in death of the affected neurons.

Frontotemporal disorders are the result of damage to neurons in parts of the brain called the frontal and temporal lobes, gradually leading to behavioral symptoms or language and emotional disorders.

Liu and her colleagues discovered that the storage of lipid droplets in glia protects neurons from damage as long as the free radicals do not destroy the lipid droplets.

ROS damage to neurons has been implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative conditions.

Misshapen proteins become entangled with neurons in prion diseases such as Creutzfeldt - Jakob disease, damaging or killing cells.

In a related study [pdf] using mice, Fornai found that lithium counteracted the damage to motor neurons brought on by the disease.

In examining autopsy samples from MS patients, the researchers detected an abundance of amyloids in brain lesions and damaged neurons, the hallmarks of the diseasIn examining autopsy samples from MS patients, the researchers detected an abundance of amyloids in brain lesions and damaged neurons, the hallmarks of the diseasin brain lesions and damaged neurons, the hallmarks of the disease.

Scientists have found that a plant pigment called quercetin — found in some fruits, vegetables, herbs and grains — could help to prevent the damage to nerves associated with the childhood form of motor neuron disease.

«In the future we are hoping to manipulate these cells to replenish any lost retinal neurons, either in diseased or physically damaged retinas,» he noteIn the future we are hoping to manipulate these cells to replenish any lost retinal neurons, either in diseased or physically damaged retinas,» he notein diseased or physically damaged retinas,» he noted.

But it also damages neurons that don't lie directly in its path, because it is trailed by a pressure wave that transfers the energy of bullet into the surrounding brain tissue.

Neuroscientists have long believed that scar tissue formed by glial cells — the cells that surround neurons in the central nervous system — impedes damaged nerve cells from regrowing after a brain or spinal cord injury.

«This solves a long - running mystery of how a gene mutation damages the neurons that carry information from the spinal cord to our muscles, resulting in a range of sensory and movement problems,» says Samuel Pfaff, a neuroscience professor at the Salk Institute and one of the senior authors on the paper with Xiang - Lei Yang, a professor at TSRI.

Unlike peripheral nerves, which re-sprout axons when they are damaged, mature spinal neurons do not regrow axons in the part of the body where the injury has occurred — such as when the spinal cord is cut or crushed — which results in paralysis below the injury.

The study, «Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits,» which has been published in The Journal of Cell Biology, suggests potential new strategies to stimulate the regrowth of human neurons damaged by injury or disease.

A small animal study suggests that high doses of the virus, called adeno - associated virus 9, can cause severe liver and neuron damage in young monkeys and pigs.

We may be able to do the same thing with similar cell lines for neurons, where we can repair the damage in the brain itself.

These problems are caused by a type of white blood cells called T cells that, after becoming activated, find their way into the brain and attack the protective covering — myelin — of neurons in the brain and spinal cord, causing inflammation and damage to the central nervous system.

The team injected about 2000 mouse embryonic stem cells each into the brains of 25 rats who had previously had their dopamine - producing neurons damaged, which causes a characteristic tendency to move in circles.

The ability to detect amyloid beta oligomers, Klein said, is important for two reasons: amyloid beta oligomers are the toxins that damage neurons, and the oligomers are the first sign of trouble in the disease process, appearing before any other pathology.

Damage to neurons in the central part of the thalamus may lead to problems with sleep, attention, and memory.

Implants can work in place of the hair cells, but if the sensory neurons are damaged, hearing is still limited.

The parasite could also directly alter neurons involved in memory and learning, or it could trigger a damaging host response, as in many human autoimmune diseases.

In humans, deafness is most often caused by damage to inner ear hair cells — so named because they sport hairlike cilia that bend when they encounter vibrations from sound waves — or by damage to the neurons that transmit that information to the brain.