Genes have the potential to become any of several types of proteins, and traumatic brain injury can damage the master genes, which can then lead to
damage of other genes.
Not exact matches
Two
other drivers — Bill Smith
of Shelter Island and
Gene Walker
of East Marion — also submitted letters to the town asking to be reimbursed for paint
damage.
Only a decade later was it confirmed to bind to DNA and turn on the expression
of other genes aimed at healing cell
damage.
Other devices and therapies in development include an implanted microchip, electrical stimulation therapy, implantable capsules
of timed - release medication, nutrient therapies to reduce retinal
damage and
gene therapies to halt or reverse retinitis pigmentosa.
In a previous study, his team worked with
other collaborators to identify the potential role
of extra copies
of the tumor suppressor
gene (p53) that increase the elephant's ability to eliminate pre-cancerous cells with DNA
damage.
In the last few years, Sweeney, a professor
of physiology and medicine at the University
of Pennsylvania, and a small cadre
of other researchers have learned how to create
genes that repair weak, deteriorating, or
damaged muscles, bones, tendons, and cartilage in a relatively short period
of time.
Biologists at the University
of California San Diego have developed a method
of manipulating the
genes of an agricultural pest that has invaded much
of the United States and caused millions
of dollars in
damage to high - value berry and
other fruit crops.
Some offspring get landed with chromosomes full
of damaged genes and are eliminated by natural selection, whereas
others inherit undamaged copies and survive to reproduce.
As in the first study, a group
of young mice carrying the human
gene APOE4 showed cognitive impairment on the behavioral level — in
other words, they showed signs
of damage on the level
of spatial memory.
Gene analyses
of the hippocampus and
other brain areas revealed dysregulation in the
genes linked to manifestation
of damaging reactive oxygen species and neuronal function.
Other genetic diseases include Tay - Sachs disease (
damage to the
gene for the enzyme hexosaminidase A leads to an accumulation
of a chemical in the brain that destroys it), sickle cell anemia (improper coding
of the
gene that produces hemoglobin), hemophilia (lack
of a
gene for a blood - clotting factor) and muscular dystrophy (caused by a defective
gene on the X chromosome).
About 5 %
of patients with colorectal cancer that has spread to
other organs have a flaw in the
genes that repair their tumors» cancer - causing DNA
damage.
Moreover, recent data also show that in response to brain
damage caused by aging, amyloid deposition, demyelination, and
other insults, microglial cells activate several
genes, including APOE, in order to more efficiently scavenge and clear tissue debris that are very rich in cholesterol due to the natural composition
of the brain, which is mostly made
of fats.
Study using disabled form
of HIV in
gene therapy wins highest award from Clinical Research Forum;
others cited for advances revealing
damage caused by long - term cortisone shots to treat arthritic knees; and
gene replacement therapy for infants with deadly neuromuscular disease
Therapy using live cells is increasingly used to replace
damaged tissue, deliver
gene therapies to target tissues and organs, and stimulate self - healing along with a number
of other applications.
The MC1R
gene is linked to
other biological processes, including repair
of DNA
damage, Gunn pointed out.
Eating turmeric in a small quantity or taking it in a dietary supplement is believed to support healthier - looking skin, including for people with eczema, psoriasis, and acne.56) The curcuminoid pigments in turmeric support
genes that enhance the body's synthesis
of antioxidants, protecting the skin and
other organs from oxidative
damage due to free radicals from environmental toxins or chronic stress.
Several years ago,
Gene Stevens and
other condo owners
of the Cricket Club Condominiums sued the Cricket Club Board
of Directors for breach
of fiduciary duty, seeking compensatory
damages from the Board because the condo owners alleged that Condo Board
of Directors spent special assessment money on things outside
of those described in the Notice
of Special Assessment that was sent to the condo unit owners.