Sentences with phrase «damage to cells over»

The oxidative stress theory of aging holds that oxidation from molecules called «free radicals» causes damage to cells over time, resulting in sarcopenia and other decline.

Not exact matches

Over a lifetime, an overactive immune system will contribute to an overproduction of AGE's, advanced glycation end products, initiating oxidative reactions within cells that will gradually damage organs throughout the body.

Researchers in France and Sweden have, over the past couple of years, shown that when BMAA is injected into rodents it gets incorporated into their eyes (pdf), where it could build up and potentially cause damage to cells in the retina.

The treatment not only led the spinal cord cells to produce and secrete ChABC in large quantities over areas spanning the injury epicenter, it helped to maintain the overall health of the damaged spinal cord and restored hind limb function in the animals within 12 weeks.

Saatchi, which is owned by France's Publicis Groupe, SA, chose LifeStraw over a field of competitors that included a reusable controller to improve the distribution of IV fluids, a collapsible wheel that can be folded down for easier storage when not in use on bicycles or wheelchairs, an energy - efficient laptop designed for children in developing countries, a 3 - D display that uses special optics and software to project a hologramlike image of patient anatomy for cancer treatment, an inkjet printing system for fabricating tissue scaffolds on which cells can be grown, a visual prosthesis for bypassing a diseased or damaged eye and sending signals directly to the brain, books with embedded sound tracks to help educate illiterate adults on health issues, a phone that provides telecommunications coverage to poor rural populations in developing countries, and a brain - computer interface designed to help paralyzed people communicate via neural signals.

Searching for a way to help people regain control over their unreliable bladders, Anthony Atala, a urologist at Children's Hospital Boston, injected stem cells from the limb muscles of rats into their deliberately damaged urinary sphincters, which control flow.

Some researchers consider normal aging to be a disease, where our cells accumulate damage over time.

Genotoxic stress — the kind that can damage a cell's DNA — causes hair to whiten over time, according to a new study.

The process must be done slowly over a period of several hours to prevent damage to the fragile cells.

Yet over the course of a life moving through this world, our DNA does get damaged, and our cells have a host of complicated repair mechanisms to deal with such injuries.

When these fatty deposits damage an artery wall, immune cells flock to the scene — notably macrophages, which gobble up dying and damaged cells all over the body.

The BET - PARP inhibitor combo represses DNA repair, allowing PARP inhibitor - induced DNA damage to take over and kill cancer cells once again.

Stem cells can morph to take on any role in the body, making them theoretically useful to treat conditions ranging from type 1 diabetes (replacing insulin - producing cells in the pancreas) to heart disease (taking over for damaged heart cells).

This meant that instead of the new cells taking over for damaged ones, they too succumbed to the not - yet - understood disease process.

Long - lived cells such as cardiomyocytes, retinal pigmented epithelial cells and neurons are particularly dependent of the efficient function of their lysosomes to prevent the accumulation of damaged macromolecules over their extended lifetimes.

Collins warned of a «cloud hanging over this field,» of top US scientists potentially being driven into other disciplines or other countries, and of «severe collateral damage» to the burgeoning field of induced pluripotent stem cell research, which, he argued, relies on human embryonic stem cells as a «gold standard» comparator.

In turn, the slow but steady buildup of damaged cells within tissues is expected to intensify DDR responses over time.

(6) However, it would be useful to see a more thorough analysis of the effect of ablating p16Ink4a - expressing senescent cells, and whether there may instead be evidence of a short - term rejuvenation of tissue function that is slowly lost over time to rising levels of other kinds of aging damage that INK - ATTAC activation does not address.

When this happens, damages to DNA accumulate over time, causing cell damage, mutation and eventually, death.

ASCs isolated from the stromal vascular fraction of fat have advantages over other mesenchymal stem cell sources; they are easy to isolate and expand and aid in the repair of damaged tissues [7], including islet graft survival and revascularization [8].

These new types of stem cells have the capacity to turn into many other cell types, holding immense promise for regenerating damaged tissues all over the body.

Only if the infection persists over time can it result in damage to cells of the cervix (which can be detected during a Pap test) and, eventually, cervical cancer.

«Increases in inflammatory activity are a very adaptive response when you have them once in a while, but to have lots of these activations over the course of a day or a week could potentially lead to chronic levels of inflammation which can be damaging to other cells and to organs.»

Over time, these white blood cells, known as foam cells, begin to invade the linings of arteries, causing further arterial damage and obstructing blood flow.

First proposed in 1972, the mitochondrial theory of aging suggests that it's free radical damage to our cells» power source, known as mitochondria, that leads to a loss of cellular activity and function over time.

some studies show even prolonged glucose above 100 damages the beta cells in the pancreas which produce insulin, which is likely part of why type 2 diabetics go from over production of insulin and insulin resistance to pancreatic insufficiency.

The chemical makeup of Astaxanthin allows it to stretch over the surface of the cell allowing it to sit near the border where damage normally occurs.

The mitochondrial theory of aging suggests that free radical damage to our cells» power source (mitochondria) leads to a loss of cellular energy and function over time.

Chronic oxidative stress — meaning chronic presence over overly reactive oxygen - containing molecules and cumulative damage to our cells by these molecules — is a risk factor for development of most cancer types.

This may have to do with vitamin E's antioxidant properties — it can help fight cell damage caused over time by things like pollution and radiation from the sun.

More damage could accumulate over time as the cell divides, which could lead to colorectal cancer.

Studies have shown that it increases neuron plasticity — the ability of brain nerve cells to take over some of the activities of brain cells destroyed or damaged by stroke.

An animal develops heatstroke when its body temperature rises to a dangerous point (often, over 106 degrees Fahrenheit) that will damage cell health and normal functions.

Free radicals cause damage to cells and DNA, which results in genetic mutations that can lead to disease over time.

Burns can range from first - degree (top layer) to third - degree burns (tissue damage), and they result in over 4,500 deaths per year due to cell death or infection or smoke inhalation.