Sentences with phrase «damage your proteins by»

Not exact matches

Its drug Niraparib kills cancer cells by inhibiting the production of proteins called PARPs, which help repair damaged DNA strands, thereby hastening the death of some types of cancer cells.

It must be noted, however, that there are injurious grain proteins that cause damage and produce symptoms by mechanisms that are as yet obscure.

These mills produce flour very quickly, but some people feel they make inferior flour because the protein is damaged by the high speed milling process.

The logic behind the raw foods movement is that the heat applied to your food during cooking damages vital nutrients and vitamins, slashing proteins and antioxidants in that food by at least half.

By adding things like salmon protein hydrolysate, damaged protein and other fillers, manufacturers are able to sell you an inferior product at an inflated price.

The presence of the S100B protein triggers the release by the body of antibodies which can then leak back into the brain through the damaged blood - brain barrier, where they are thought to attack brain tissue.

Others note that shear forces from shaking are not the only issue — bursting of bubbles caused by shaking may also damage cells or denature proteins.

Results of the new study build on previous findings by Hackam's team showing that a protein called TLR4 (toll - like receptor 4) is a key instigator of the intestinal damage seen in NEC.

Findings of the research, published April 22 in the journal Mucosal Immunology, reveal that a substance found in animal and human breast milk called epidermal growth factor, or EGF, blocks the activation of a protein responsible for unlocking the damaging immune cascade that culminates in NEC, a disease marked by the swift and irreversible death of intestinal tissue that remains one of the most - challenging - to - treat conditions.

The test, which could be available to patients within two years, identifies the chemical signatures found in the plasma of blood joint proteins damaged by oxidation, nitration and glycation; the modification of proteins with oxygen, nitrogen and sugar molecules.

The p53 protein helps keep cancer in check by ordering a cellular mop - up in response to DNA damage.

Dartmouth researchers previously demonstrated that STK17A is a protein that is induced when DNA is damaged by the chemotherapeutic drug cisplatin.

One is that the cancer - related proteins used by the test reflect tissue damage and can also appear in people with inflammatory diseases such as arthritis.

«The damage caused by the mutant huntingtin protein radiates out through the cell, like a pebble dropped in a pond.

Many scientists believe that the aging process is caused by the gradual buildup of a huge number of individually tiny faults — some damage to a DNA strand here, a deranged protein molecule there, and so on.

Proteins are produced by ribosomes, and misfolding can occur if they stall while decoding a damaged template.

But Frankovich and her Stanford colleagues were dealing with something else: damage caused by the immune response, including antibodies, the large Y - shaped proteins the body produces to fend off infections or other foreign invaders.

«Prion proteins with a trimmed version of the flexible tail can, however, no longer damage the brain cells, even if their switch has been recognized by antibodies,» explains Adriano Aguzzi.

A new study suggests that in mice, cutting protein from the diet for a week can protect organs that might otherwise be damaged by injury or surgery.

«Our data clearly showed that one of the protein receptors on white blood cells called CXCR3 brings white blood cells to the optic nerve in response to production of its binding partner CXCL10 by damaged nerve tissue,» said Zhang.

An earlier study indicated that the intermediate step was likely a floppy loop area formed by proteins, which didn't seem compatible with the tough, damaging fibril as an end result.

They nicknamed it «Delta 20,» an immune system protein that suppresses the most damaging HIV strains, X4, by preventing the virus from infecting cells.

They try to outdo other suitors by spiking seminal fluid with proteins that kill other flies» sperm — with collateral damage to the female.

By turning down the dial on protein production, the diseased and damaged neurons were able to survive longer.

But the molecules also affect the cells of the animal ingesting the food, by damaging the DNA, proteins, and other critical parts of the cells in their body.

Wyrick and his colleagues also saw less damage around transcription factors, proteins that bind to specific, short stretches of DNA and regulate gene expression by controlling which genes are turned on and off.

AMD develops slowly over decades, with the buildup of fatty protein deposits in the retina, which cause damage by blocking the flow of nutrients into the light - sensitive portion of the eye, and of waste products out.

The protein, called Bcl - 2, is already famed among biologists for its ability to block «apoptosis,» or cell suicide, the process by which damaged or obsolete cells destroy themselves.

A group of researchers at Osaka University found that if DNA damage response (DDR) does not work when DNA is damaged by radiation, proteins which should be removed remain instead, and a loss of genetic information can be incited, which, when repaired incorrectly, will lead to the tumor formation.

Most MGUS cases are never diagnosed; MGUS is characterized by a detectable M protein without evidence for end - organ damage or other related plasma cell or lymphoproliferative disorders.

Neurons try to avoid this damage by secreting these lipids, and apolipoproteins — proteins that transport lipids — carry them to glia cells.

The protein produced by this gene protects the chromosome ends of the DNA from damage, and controls telomere maintenance by the telomerase enzyme.

Now, researchers at Washington University School of Medicine in St. Louis have identified a compound that targets the APOE protein in the brains of mice and protects against damage induced by the Alzheimer's protein amyloid beta.

What these illnesses have in common is that they're caused by abnormal proteins that accumulate in or between brain cells to form plaques, producing damage that causes mental decline and early death.

They found that the cell recycling machinery is regulated by a protein called WHAMM, and that interfering with this protein or actin polymerization itself severely inhibits the cell's ability to recycle misfolded proteins and damaged organelles via autophagy.

They found that by attaching to a mitochondrial protein called TOM20, alpha - synuclein prevented the mitochondria from functioning optimally, which resulted in the production of less energy and more damaging cellular waste.

Conclusion: Researchers observed reductions in markers of muscle damage and improved athletic performance in subjects taking the whey protein, HMB, and isomaltulose supplement, suggesting that whey protein supplementation can be optimized for muscle recovery during intense conditioning by adding HMB and a slow - release carbohydrate.

Based on mouse studies, the researchers suspect that the cone cells of people with achromatopsia are not permanently damaged and could be revived by enhancing the pathway that regulates the unfolded protein response.

This leads to an increased risk of DNA damage, followed by attachment of a protein named yH2AX to the damaged stretches of DNA.

RIPK1, the researchers found, inflicts damage by directly attacking the body's myelin production plants — nerve cells known as oligodendrocytes, which secrete the soft substance, rich in fat and protein that wraps around axons to support their function and shield them from damage.

When this protein is damaged or missing, it changes the activity of multiple genes and causes Rett syndrome, a disorder marked by developmental delays, seizures and autism - like behaviors.

That's good for probing delicate samples, such as proteins, than can be damaged by high - intensity light.

Physiologically, the growth factors interact with these proteins to stimulate cell growth in damaged tissues by activation of receptors.

Manipulating proteins in the body to compensate for the lack of dystrophin is one of many strategies being investigated to halt or reverse the muscle damage caused by DMD.

«How nerve cells are damaged by accumulation of abnormal proteins.»

In most cases, CTE is thought to be caused by repeated blows to the head, which damage brain tissue and lead to a buildup of an abnormal protein called tau, according to the CTE Center.

They have now discovered that the protein is released by damaged cells and is then truncated by enzymes secreted by mastocytes, white blood cells that are key factors in allergy.

Even though cells are not threatened by hurricanes and earthquakes, the damage induced by heat or radiation is equally devastating: Important proteins that control chemical reactions, transport substances or recognize signal substances, among others, lose their structure and are rendered useless.

Carney and his colleagues also discovered that the brains of older gerbils tend to contain higher levels of proteins that have been damaged by free radicals than those of younger gerbils, again suggesting their importance in ageing.

After two earlier published attempts that led to early - stage embryos but not confirmed embryonic stem cells, Mitalipov and colleagues took steps to preserve a protein complex believed to help primate eggs restructure transplanted DNA, and employed a new imaging system to observe the egg's chromosomes directly instead of by staining them or using ultraviolet light, which might damage DNA.