Those cells hold an original and intact DNA copy which can be used to replace
damaged cells if necessary.
Brains of people who died from various diseases caused by tangled tau had more dead and
damaged cells if the people carried APOE4.
Not exact matches
Yeo explained that you need to prepare someone's finger for this process to make sure blood is flowing, but
if you end up squeezing the finger too hard or have to prick it too many times, that may
damage and break down
cells — and this cellular
damage could skew various test results.
By paying your monthly
cell phone bill with the Uber credit card, you will be reimbursed for up to $ 600 in losses
if your phone is
damaged or stolen.
Now,
if we are not going to outlaw abortion, and the doctors / scientists want to take the aborted fetus and do stem
cell research on it, well the
damage is done and we might as well get all that we can out of it.
If you can't follow that logic, then you should just stop trying to think, you might
damage the two functional brain
cells you have left
The
cells of your body have their own little wills to live, so they will carry you along to some extent; but
if you do not want to live,
if you do not get any satisfaction out of living, you'll not live long, and you'll do a lot of
damage to yourself psychologically.
Also, even
if some
damage to my foot is responsible for the ache,
if the subjective experiences of the
cells in my foot in fact bear no relation to the experience I feel as an ache, then there is no truth relation.
If a
cell is too
damaged by free radicals,
Peanut butter only contains 1 milligram, so your
cells won't be getting much protection from oxidative
damage if you are opting for that nut butter all the time.
Then that
cell (now a free radical) goes and steals an electron from another healthy
cell which essentially starts a free radical cascade that can cause serious DNA
damage if it continues.
As a result of this, their bodies will release a lot of free radicals that
if not eliminated, will cause
damage to the surrounding
cells and tissues.
If the tumor that Jobs had removed in 2004 had begun to break down prior to the surgery, White says, the tumor's dead
cells could have released protease and lipase enzymes that may have
damaged beta
cells in the pancreas, which produce insulin.
If they succeed, they can be reasonably confident that epithelial
cells can be taken from a patient and used to regenerate
damaged tissue in that same person.
However,
cells could only be saved
if they were treated within 10 days of being
damaged.
These are receptors on immune
cells, which control for example effector T -
cells by dampening their activation
if damage to healthy
cells is imminent.
«Before this study, it was not known
if it is possible to produce sufficient numbers of these
cells and successfully use them to remuscularize
damaged hearts in a large animal whose heart size and physiology is similar to that of the human heart,» said Dr. Charles Murry, UW professor of pathology and bioengineering, who led the research team that conducted the experiment.
We know that they are under stress when they are fighting cancer or other diseases, so I wondered whether anything measureable could be seen
if we put them under further stress with UVA light.We found that people with cancer have DNA which is more easily
damaged by ultraviolet light than other people, so the test shows the sensitivity to
damage of all the DNA — the genome — in a
cell.»
If that
damage is deemed too extensive by other cellular actors that interact with p53, it triggers p53 to launch the call for the
cell to commit suicide.
If this environment is harmed by chemicals, such as through
damage to gut
cells, it could impact the health of the organisms and would lead to a number of fish diseases but this technique will enable us to increase the tests we can carry out and improve our understanding of how to preserve gut health.»
If a
cell is frozen, radiation does less
damage to it because the free radicals it creates are much less mobile.
«Prion proteins with a trimmed version of the flexible tail can, however, no longer
damage the brain
cells, even
if their switch has been recognized by antibodies,» explains Adriano Aguzzi.
Now, with new kinds of technologies that are coming up, new types of tissue engineering and, you know, some of the hopes that people have for stem
cells and [the] like, it may be interesting to see
if there are other ways, alternatives to dealing with really badly
damaged hearts that would involve growing a new heart or replacing or repairing the
damage d to a badly
damaged heart that might make artificial hearts less important in the somewhat more distant future.
If we introduced stem
cells with nice, long telomeres in the first place, we could let them wind down and eventually be lost to apoptosis, senescence, or other sources of
damage — and just top our tissues up with more stem
cells before enough of those
cells were lost to begin to impair tissue function.
Now, the researchers have discovered an alternative in a mouse model: in the case of breast tumours with a specific defect in DNA repair, the animals can be cured using already established, cheap chemotherapy drugs,
if enough DNA
damage can be inflicted on the resting tumour
cells.
Unlike mammals, birds can quickly regenerate hair
cells in the inner ear
if they become
damaged.
If the yeast's ribosomes jammed on the oxidized mRNA but were rescued by no - go decay, very little
damaged mRNA would accumulate in the
cell.
But
if the factors involved in this quality - control system were absent,
damaged mRNA accumulated in the
cell, just as it does in Alzheimer's.
It is therefore essential that there be control mechanisms capable of detecting errors in this process and halting the
cell cycle with the aim of allowing the
cell to repair the breakages or,
if not possible, to eliminate the
damaged cell.
But
if children near Chernobyl received a lower dose, it could have
damaged their DNA without killing the
cells.
Because our
cells are made up of mostly water,
if we dehydrated them to the point of having no fluid, they would be
damaged by so - called solution effects, which result from the
cell being too concentrated and not having its water replaced by some other compound.
But
if the plaque buildup continues, the immune response may escalate into overaggressive inflammation that further
damages the arteries and clogs them with bits of plaque and dead immune
cells.
Such
cells might one day be used to treat people with
damaged lung tissue, but only
if the
cells can be made from a person's own tissue.
It can sense the presence of DNA
damage, signal to other proteins that
damage exists, aid in the repair of
damage and stimulate
cell death
if the
damage can not be repaired.
In human
cells as well,
if Nbs1 and ATM function in the same way to ensure repair of DNA
damage, tumor formation may be prevented.
Vanamala suggests that BMI - 1 stem
cells may become cancerous
if exposed while moving up the crypt to heal
cells and are
damaged by inflammation and toxins produced by eating a high - calorie diet.
One of the genes that MM41 blocks — the BCL - 2 gene — is involved in regulating apoptosis, the body's natural process which forces
cells to die
if they become too
damaged or unhealthy to be repaired.
And
if apoptosis fails to destroy
damaged cells in adults, it can lead to cancer.
But
if the HLA - A2 gene turns out to be the culprit, then the immune system is probably involved somehow in Alzheimer's symptoms, says Payami, perhaps by
damaging nerve
cells.
If DNA
damage persists for a very long time the
cells may eventually turn the checkpoints off without waiting for the DNA to get repaired.
It prevents
damaged cells from reproducing by stopping their growth until the
damage is repaired or,
if the
damage can not be reversed, promotes
cell death.
«
If you kill the
damaged cell, it's gone, and it can't turn into cancer.
Wilson says the team next plans to investigate
if lithium chloride can blunt other forms of neurological
damage, such as that resulting from trauma and stroke, both of which can kill large groups of brain
cells.
«We don't know for certain
if the
damage is irreversible, but I expect so, because the
cells that hold the internal structure in place have been infected and destroyed,» said Diamond, who is also a professor of pathology and immunology, and of molecular microbiology.
«
If you get CD8 T
cells that are hyperactivated they can cause a tremendous amount of
damage.»
According to Munsey Wheby, president of the American College of Physicians, excess fat deposited in the liver is thought to trigger the production of inflammatory molecules that
damage cells and ultimately —
if left unchecked — lead to cirrhosis.
«There are not many,
if any, known systems which can be used to restore cardiovascular endothelial
cells which are already
damaged, and Vitamin D3 can do it,» Malinski said.
The researchers say their next step is to transplant the
cells into mice with spinal cord injuries to see
if the V2a interneurons can help to restore movement after
damage has occurred.
«The mammary gland has a huge amount of stuff that it has to get rid of quickly after lactation, but
if you just have immune
cells taking the dead
cells out, you still get chronic inflammation and tissue
damage,» says Charles Streuli, who supervised the study.
To see
if this same result held true in higher organisms, Gerton's team treated cancer
cells from Li's mice with four different DNA
damaging drugs.