Sentences with phrase «damaged photoreceptor cells»

GenSight's treatment is for people with damaged photoreceptor cells but intact ganglion cells; it inserts the gene into the ganglion cells, whose axons form the basis of the optic nerve.

Not exact matches

The artificial retina then converts the signal into electrical impulses, which bypass damaged photoreceptors and stimulate the retina's remaining cells.

In people with RP and AMD, the photoreceptors have been damaged and lost, so the ganglion cells do not receive signals and the brain can not produce an image.

Bypassing damaged retinal cells The light - sensitive photoreceptors made by the rod and cone cells in the retina also belong to the GPCR class.

Functional damage to these photoreceptors, or pathological loss of the cells that bear them, results in inability to register light impinging on the retina — and is responsible for various types of visual impairment and certain forms of congenital blindness.

They play a pivotal role in regulating synaptic transmission, modulating excitotoxicity responsible for much of the neuronal damage caused by hypoxic insult in the brain [37], and are expressed in retinal photoreceptors, horizontal cells, and bipolar cells as well as the amacrine and ganglion cells of the inner retina [38 — 41].

In retinal diseases such as age - related macular degeneration, for example, photoreceptor cells that absorb light signals are damaged or dead.