Sentences with phrase «damaging effects of mutation»

Researchers at the University of Oxford have discovered that a cellular mechanism preferentially protects plant genes from the damaging effects of mutation.

Not exact matches

On the other hand, without high levels of suPAR, the ability of the genetic mutation of APOL1 to exert its damaging effects is impaired, which helps identify patients in most need of suPAR lowering or future anti-suPAR therapy.

This suggests that the absence of DJ - 1 was unlikely to have strongly accelerated mtDNA damage caused by the Polg mutation, although we can not exclude a more subtle effect.

If we can develop therapies that help them fight off the negative effects of the mutation, we're hopeful that people could expect more healthy years, thanks to the remarkable ability of the brain to cope with damage.

«Many of the carcinogens present in mainstream smoke are known to exert their effects through a genotoxic mode of action, which is based on their ability to induce DNA damage and mutations, although an epigenetic mode of action, e.g., through aberrant DNA methylation and histone modifications, is also beginning to emerge for a few of these carcinogenic compounds.»