The parasite could also directly alter neurons involved in memory and learning, or it could trigger
a damaging host response, as in many human autoimmune diseases.
Not exact matches
The analysis also showed that the preponderance of
host responses shifted rapidly from activation of genes involved in cell
damage and inflammation toward those linked to promotion of cellular and organ repair.
The Cell
Host & Microbe study suggests a way to circumvent the
damaging autoimmune
response triggered by strep.
The force of that blood flow helps keep the cells that line the blood vessels, called endothelial cells, healthy; when blood flow is disrupted, such as during surgical procedures or a stroke, the vessels start to leak, which can cause a
host of inflammatory
responses that lead to cell
damage and disease.
Sepsis, Drs. Tracey and Deutschman wrote, «is not a stereotypical, steadily progressive immunological process that follows infection or injury; that innate and adaptive immune
responses do not inevitably
damage host cells; and that the long - held notion that sepsis is a distinct immunological disorder is incorrect.
8.30 Hana Paculová CDK12 connects transcriptional regulation to DNA
damage repair pathway 8.55 Karol Kaiser Wnt secretion during nervous system development 9.20 Simona Hankeová The role of Notch signaling in vasculogenesis 10.00 Coffee break 10.30 Tomáš Doležal Extracellular adenosine regulates complex
host - pathogen interactions through the energy release for the immune
response 10.55 Ondřej Bernatík and Igor Červenka Regulation of diverse function of Dvl by phosphorylation 11.20 Jan Ryneš Dissection of Axin interactome: rational approach for control of signaling cascades via intervention with specific protein - protein interactions 12.05 Targeting opportunities: discussion & sum - up 13.00 Lunch and departure
In order to prevent autoimmunity and «collateral
damage» to
host tissues in the course of
responses to pathogens, innate and adaptive immunity are subject to stringent control mechanisms.
The group focuses on endogenous mechanisms that control (i.e. limit) immune
responses in vivo and thereby prevent inflammatory disease caused by immune - mediated
damage to
host tissues.
Herpes simplex virus 1 (HSV - 1) has extensive interactions with the
host DNA
damage response (DDR) machinery that can be either detrimental or beneficial to the virus.
The cellular
damage from over exercising triggers a systemic inflammatory
response that sets the stage for a
host of other health problems.
We'd like to thanks our sponsors Facebook, Fourth Floor Creative, Splash
Damage, Riot Games, Amiqus, OPM
Response, Sumo Digital and Ukie for making this night a huge success, as well as our incredible
host Dr Jo Twist OBE, CEO of Ukie.