Many trials have used viruses as carriers, but this approach has run into problems with toxicity and
dangerous immune system responses.
Not exact matches
«Instead of mounting a tolerant, non-aggressive
response, the
immune system in the presence of the reovirus views gluten as being
dangerous, promoting a destructive inflammatory
response,» says Jabri.
The answer is complicated, he adds, but much of it involves a delicate balancing act among elements of the
immune system: while immunity protects us against disease, an overly aggressive
immune response may trigger
dangerous, even life - threatening, autoimmune reactions in which the body attacks itself.
The vaccine, if effective, would be given in two doses, one to prime the
immune system to recognize these
dangerous invaders, and a booster shot of a different vaccine that would amplify the
immune response.