Sentences with phrase «data on current conditions»

They particularly stressed the need to develop a comprehensive observation system for obtaining data on current conditions and ongoing developments in the Arctic region.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Among the likely changes to Dodd - Frank: raising the threshold for tougher oversight from the current $ 50 billion in assets to $ 250 billion; exempting small banks from the so - called Volcker rule, which currently bars them from speculative trading; reducing the amount of financial reporting, particularly racial and income data on mortgage holders; lowering the frequency of regulatory exams; and easing the conditions of stress tests.

The pro forma consolidated balance sheet data gives effect to (i) the automatic conversion of all of our outstanding shares of convertible preferred stock other than Series FP preferred stock into shares of Class B common stock and the conversion of Series FP preferred stock into shares of Class C common stock in connection with our initial public offering, (ii) stock - based compensation expense of approximately $ 1.1 billion associated with outstanding RSUs subject to a performance condition for which the service - based vesting condition was satisfied as of December 31, 2016 and which we will recognize on the effectiveness of our registration statement in connection with this offering, as further described in Note 1 to our consolidated financial statements included elsewhere in this prospectus, (iii) the increase in accrued expenses and other current liabilities and an equivalent decrease in additional paid - in capital of $ 187.2 million in connection with the withholding tax obligations, based on $ 16.33 per share, which is the fair value of our common stock as of December 31, 2016, as we intend to issue shares of Class A common stock and Class B common stock on a net basis to satisfy the associated withholding tax obligations, (iv) the net issuance of 7.6 million shares of Class A common stock and 5.5 million shares of Class B common stock that will vest and be issued from the settlement of such RSUs, (v) the issuance of the CEO award, as described below, and (vi) the filing and effectiveness of our amended and restated certificate of incorporation which will be in effect on the completion of this offering.

The data is unambiguous on current economic conditions - GDP growth in the last quarter of 2015 was a meager 2.11 % with full year growth of 2.79 % according to the National Bureau of Statistics (NBS); inflation rose sharply to 11.4 % in February with prospects of reaching 12 % by March; capital markets have remained bearish; according to UNCTAD Nigeria's FDI fell by 27.7 % to $ 3.4 billion in 2015, and on current trends may fall even more precipitously in 2016; the de facto exchange rate of the Naira for most producers and consumers is now N322 / $ even though CBN maintains a nominal N197 / $ for privileged persons; several economic sectors - construction, government, manufacturing, oil and gas and hotels and restaurants are in recession or barely out of it; government's official foreign reserves is down to $ 27.8 bn; and unemployment and under - employment rates have worsened 10.4 % and 18.7 % by the end of 2015.

Otte: «In its current form the memory can operate only in very clean vacuum conditions and at liquid nitrogen temperature (77 K), so the actual storage of data on an atomic scale is still some way off.

The new findings of successful multi-year drought / fire predictions are based on a series of computer modeling experiments, using the state - of - the - art earth system model, the most detailed data on current ocean temperature and salinity conditions, and the climate responses to natural and human - linked radiative forcing.

Balazs and his colleagues report in the current issue of the Marine Pollution Bulletin how 300 pellets a day were washing up on Kualoa Beach: «A general review of data for tidal cycles, moon phases, wind speed and direction, and surf conditions failed to identify any consistent correlation with the erratic fluctuations in daily faecal counts.»

We Recognize that to improve means we must consistently and accurately assess current conditions of our schools based on appropriate data that aligns with our national goals.

Kelley Blue Book residual values are based on current vehicle data, market conditions for each vehicle, expectations for the future economy and the combined experience of Kelley Blue Book's experts.

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At the beginning, and before any running takes place, the team of vets will check each dog and compare the data on the certificate supplied on entry with its current condition.

Based on this data, the study authors concluded, «These findings supported current guidelines that recommend vaccination of all cats immediately after admission to animal shelters, regardless of the source or physical condition.»

When local observational data, scientific studies and engineering professionals all agree that current sea level rise is at historical average (albeit showing a statistically insignificant decline) I think we can put off spending on further research until our conditions warrant.

But this is in a period that the Bureau has predicted is likely, based on statistical analysis of historical data and current sea surface conditions, to be warmer than the historical average (see here.

The main reason for this App is to make a lite, fast Facebook App for Low - end Android smartphones, as the current Facebook App is very large in size and performs slow on low - spec devices with less Ram and CPU power and uses less data and works in all network conditions

Optimized trading strategies based on current market conditions, analysis of post trade data, improving strategy parameters and researching information relevant to the market.

MLS — the creation, managing, entering the data, monthly internet costs Legal forms — the creation, understanding the «legal» forms, cost for them Opinion of Value — comparables and current market conditions Education — never ends when you get you're licence; should always be active with the economy, mortgage rates, new by - laws; the list goes on Time — dealing from the first call, to the appointment, checking into information if need be, confirming all information is correct, and then having the system in place to bring active buyers to their home Insurance — somebody should have insurance — the Realtor pays Advertising — cost to advertise — not cheap Office supplies — from the paper, ink, signs and posts on the front lawn, computers, printers, monthly internet fees... and the list goes on...