Not exact matches
Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of
data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing
on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in
economic and business
conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report
on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC)
on February 26, 2018, and is available
on the SEC's website at www.sec.gov.
In addition to the rules - based approach, Mester also suggested the Fed not focus so much
on short - term
data changes in its
economic projections, and tweaking those projections to link them to where each individual member believes the funds rate should be if those
conditions come to fruition.
However, section of the minutes focusing
on policy normalization highlighted many policymakers» willingness to wait for more
data and assess
economic conditions.
As for what this means for the timing of a Federal Reserve (Fed) rate hike,
data about the U.S. economy
on balance exceed the reasonable measures a «
data dependent» Fed might require to move off of «emergency interest rate» levels, as BlackRock's proprietary «Yellen Index» of labor market /
economic conditions shows in the chart below.
Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general
economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these
conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in
data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance
on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report
on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.
Estimates are based
on the analysis of various elements related to the ad spending market, including macro-level
economic conditions; historical trends of the advertising market; historical trends of each medium in relation to other media; reported revenues from major ad publishers; estimates from other research firms;
data from benchmark sources; consumer media consumption trends; consumer device usage trends; and eMarketer interviews with executives at ad agencies, brands, media publishers and other industry leaders.
The
data is unambiguous
on current
economic conditions - GDP growth in the last quarter of 2015 was a meager 2.11 % with full year growth of 2.79 % according to the National Bureau of Statistics (NBS); inflation rose sharply to 11.4 % in February with prospects of reaching 12 % by March; capital markets have remained bearish; according to UNCTAD Nigeria's FDI fell by 27.7 % to $ 3.4 billion in 2015, and
on current trends may fall even more precipitously in 2016; the de facto exchange rate of the Naira for most producers and consumers is now N322 / $ even though CBN maintains a nominal N197 / $ for privileged persons; several
economic sectors - construction, government, manufacturing, oil and gas and hotels and restaurants are in recession or barely out of it; government's official foreign reserves is down to $ 27.8 bn; and unemployment and under - employment rates have worsened 10.4 % and 18.7 % by the end of 2015.
All over the world, groups and individuals are using technology in a variety of innovative ways to increase government transparency, fight corruption, open
data, hack
on civic problems, strengthen
economic development, address environmental problems, improve public health and education, and advance the
conditions of women and children.
2012 KIDS COUNT
Data Book The Annie E. Casey Foundation's new 2012 KIDS COUNT
Data Book finds that, despite the increasing
economic hardship
on U.S. families, students» academic achievement and health
conditions have improved in most states.
Stocks however, you have to factor in the sentiment towards a sector, you have to have a grasp
on a companies fundamentals, and even have a beady eye
on economic data and overall market
conditions.
But
data from earlier times can be dismissed
on the grounds that the
economic conditions under which that
data was produced no longer...
a) they don't believe the premise of man - made climate change: they don't think scientific
data collected to date is adequate to prove conclusively that any type of man - made event can result in either the recent fluxuations in climate or the anticipated kinds of drastic climate change, therefore CO2 control would be ineffective at solving the problem b) they don't believe CO2 alone is responsible: they think other variables are as or more likely to be the catalysts or causes for the scientific
data collected to date
on climate change therefore CO2 control would be ineffective at solving the problem c) they believe government efforts to curb CO2 emissions will fail resulting in an unprecedented waste of money and worse
economic conditions.
TGICA oversees a
Data Distribution Centre (DDC) which provides data sets, scenarios of climate change and other environmental and socio - economic conditions, and other materials (e.g. technical guidelines on the use of scenarios and fact sheets offering clarifying explanations / concise guidance on topical issu
Data Distribution Centre (DDC) which provides
data sets, scenarios of climate change and other environmental and socio - economic conditions, and other materials (e.g. technical guidelines on the use of scenarios and fact sheets offering clarifying explanations / concise guidance on topical issu
data sets, scenarios of climate change and other environmental and socio -
economic conditions, and other materials (e.g. technical guidelines
on the use of scenarios and fact sheets offering clarifying explanations / concise guidance
on topical issues).
Strengthen their commitment to the free and unrestricted exchange of meteorological and related
data and products; Increase the volume of
data and products exchanged to meet the needs of WMO Programs; Assist other Members, to the extent possible, and as agreed, by providing additional
data and products in support of time - sensitive operations regarding severe weather warnings; Strengthen their commitments to the WMO and ICSU WDCs in their collection and supply of meteorological and related
data and products
on a free and unrestricted basis; Implement the practice
on the international exchange of meteorological and related
data and products, as described in Adopts (1) to (3) above; Make known to all Members, through the WMO Secretariat, those meteorological and related
data and products which have
conditions related to their re-export for commercial purposes outside of the receiving country or group of countries forming a single
economic group; Make their best efforts to ensure that the
conditions which have been applied by the originator of additional
data and products are made known to initial and subsequent recipients; *» Free and unrestricted» means non-discriminatory and without charge.
While increasing the volume of
data and products available to all Members by providing these additional
data and products, it is understood that WMO Members may be justified in placing
conditions on their re-export for commercial purposes outside of the receiving country or group of countries forming a single
economic group, for reasons such as national laws or costs of production; Members should provide to the research and education communities, for their noncommercial activities, free and unrestricted access to all
data and products exchanged under the auspices of WMO with the understanding that their commercial activities are subject to the same
conditions identified in Adopts (2) above; Urges Members to:
This product combines historical
data on crop growth and fieldwork
conditions with
economic considerations to determine best / worst / average scenarios of successfully completing nitrogen applications within a user - specified time period.
The firm's estimates are based
on a model which observes
data culled from major publishers,
economic conditions, discussions with stakeholders, and past trends and performances.
Blocknubie builds highly personalised roadmaps based
on the blockchain concept, company and
economic conditions, location, market
data and funding requirements.
Appraisals of the need for special measures should be carried out
on the basis of accurate
data, disaggregated by race, colour, descent and ethnic or national origin and incorporating a gender perspective,
on the socio -
economic and cultural 35status and
conditions of the various groups in the population and their participation in the social and
economic development of the country».
To collect, analyze and disseminate
data / information
on significant market,
economic, demographic and technological
conditions affecting the housing and real estate industry.
Although consumer expenditures
on major appliances and furniture are a relatively small share of total expenditures, the
data can help demonstrate the relationship between these types of expenditures and broader
economic conditions.