Taken together
our data support a model in which ES cell culture has trapped a set of interconvertible cell states reminiscent of the early stages in blastocyst differentiation that may exist only transiently in the early embryo.
Models are fine to depict the real world, as long as scientific
data supports those models.
Not exact matches
Jonathan Niednagel, Vice President New Market Development at Prevalent Inc., a supplier of third - party risk management technologies, puts it this way: «It will take several years of breach
data before the underwriters are able to build
models that
support their pricing structure.
The others are organizational enablers: building the talent, culture and operating
model to
support digital success; developing capabilities to bring Big
Data and analytics into decision making; and rebooting the IT backbone to free it from its slow - moving legacy past.
Yesterday Channel 4 News reported that it had been able to obtain some of the
data Kogan
modeled for CA — thereby
supporting Wylie's testimony that CA had not locked down access to the
data.
Built on a unified
data model and clinical intelligence, RxAdvance's PBM standard services include Benefit and Formulary Design, Claims Processing, Customer
Support Services, Retail Pharmacy Network Management, Clinical Services, and Rebate Management.
Among the
data that drives this tool is NOAA's topography
data — a fundamental element in their wetlands restoration
model for informing industrial investment decisions that
support not only bottom line for manufacturing but the environment.
For now, however, the Fed appears willing to look through the soft inflation
data, sticking with the view that inflation will move back towards 2 %,
supported by a tight labor market and a Philips curve
model for inflation.
So, it is indeed very nice to get
data that
support your
model but you make the best progress by getting a result that disproves you
model so you make a new one that is CLOSER to the truth.
The beauty of evolutionary biology is that unlike physics, where you have to take a ton of
data to hope that the one
model you've got really works, evolution allows you to pull together pieces from hundreds of different areas of search to all
support the same theory.
Both Scripture and tradition contain much
data to
support the use of process
models in the development of a Christian theology.
We chose to
model the effects on body weight because good evidence (from both trials and epidemiological studies) links regular consumption of sugar sweetened drinks to weight gain.8 10 12 Moreover,
data from longitudinal studies
support the idea that changes in the price of sugar sweetened drinks are linked to changes in body weight.20 Other groups have used this form of
modelling to estimate the effects of a sugar sweetened drink tax on obesity.18 21 22
There are no
data to
support applying the same ratings to other sized helmets of the same
model, including youth football helmets.
Although not directly comparable, our findings are in broad agreement with those from routine
data in Scotland that have indicated a positive association between Baby Friendly accreditation, but not certification, and breastfeeding at 1 week of age.17 Our findings reinforce those of Coutinho and colleagues who reported that high exclusive breastfeeding rates achieved in Brazilian hospitals implementing staff training with the course content of the Baby Friendly Hospital Initiative were short - lived and not sustained at home unless implemented in combination with post-natal home visits.35 Similarly in Italy, training of staff with an adapted version of the Baby Friendly course content resulted in high breastfeeding rates at discharge, with a rapid decrease in the days after leaving hospital.36 In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention
modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal
support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based intervention.
We had a really nice theoretical
model in the nineties and some of the
data seemed to
support it, but the more
data we got, the muddier the waters became, says Luisa Rebull of NASA's Spitzer Science Center in Pasadena, Calif., lead author of the paper that appeared in The Astrophysical Journal July 20.
The researchers report online today in Nature Geoscience that the findings from that climate
model were
supported with
data from 18 other
models.
The researchers found that by making tweaks to specific assumptions in the
model, they could effectively force the
model to make predictions that
supported one government spending camp or the other — even if they used the exact same
data.
Biomolecular
model based on the gene expression
data analyses
support the reduction of glucose molecules (blue gradient) and acid buildup (gold gradient) proposed to occur in the boundary layer around the cell.
This illustration shows a compact
model of the heliosphere,
supported by this latest
data.
Working with colleagues at the Flowminder Foundation and
supported by the Bill and Melinda Gates Foundation, the researchers have used census micro-
data (anonymised census information at the individual level) to
model estimates of migration flows within countries and then produced a series of maps to visually represent the
data.
The campaign is
supported by ground - based measurements at various stations, analysis of satellite
data, and
model calculations.
Data from three
model systems
support the hypothesis that L - arginine - derived nitrogen oxides (NOs) mediate insulin release stimulated by L - arginine in the presence of D - glucose and by the hypoglycemic drug tolbutamide.
There are lots of computer
models showing that this could happen, but no real - life
data on food shortages to
support the idea.
Though mutations that cause human cancer have traditionally been thought to originate from heredity or environmental sources, these results — grounded in a novel mathematical
model based on
data from around the world —
support a role for so - called «R» or random mutations in driving the disease.
«The critical next step is to study this biological mechanism in a mammalian
model and generate
data to
support a clinical trial of rapamycin or a related drug for DCM patients who have these genetic variants.»
Alan Guth, a physicist at the Massachusetts Institute of Technology who pioneered the concept of inflation, says the analysis is convincing, but not so convincing that he's ready to abandon the possibility that BICEP2's
data holds a signal in
support of more obscure
models of inflation.
Lonnie Thompson, Distinguished University Professor in the School of Earth Sciences at The Ohio State University and co-leader of the international research team, said that the new
data lend
support to computer
models of projected climate changes.
Cloud computing offers an agile delivery
model and a highly scalable infrastructure to
support the demands for storage and computation of big
data technologies.
Though promising, the
model needs more
data regarding air circulation patterns and vegetation types to
support it, Sheil notes.
The researchers found that the Chandra
data from Sgr A * did not
support theoretical
models in which the X-rays are emitted from a concentration of smaller stars around the black hole.
The ARM Facility is looking to the future and undergoing a reconfiguration that will enhance the application of ARM
data to
support process studies and accelerate
model development.
Our
data suggest that certain presumed null alleles, although unable on their own to
support basal transcription, may in fact have a substantial impact on disease outcome in compound heterozygous humans, as they do in mouse
models.
It provides a wealth of information on good practices in the use of mouse
model (standardized techniques, ethics, regulations, analysis,
data and resources...) to
support attendees in their research.
Sponsor: This research was
supported by the U.S. Department of Energy Office of Science, Office of Biological and Environmental Research as part of the Earth System
Modeling program, and used
data from the ARM Climate Research Facility.
Objective: To provide
data - driven and computational infrastructures and
data - sharing platforms to
support large - scale, system - level
data integration and
modeling, and enable predictive biology for pathogens and host - pathogen interactions for discovery research, clinical investigation, and therapeutic development for infectious diseases.
These
data substantially increase existing knowledge of synapse protein phosphorylation and
support a
model where the synapse phosphoproteome is functionally organized into a highly interconnected signaling network.
-- 7) Forest
models for Montana that account for changes in both climate and resulting vegetation distribution and patterns; 8) Models that account for interactions and feedbacks in climate - related impacts to forests (e.g., changes in mortality from both direct increases in warming and increased fire risk as a result of warming); 9) Systems thinking and modeling regarding climate effects on understory vegetation and interactions with forest trees; 10) Discussion of climate effects on urban forests and impacts to cityscapes and livability; 11) Monitoring and time - series data to inform adaptive management efforts (i.e., to determine outcome of a management action and, based on that outcome, chart future course of action); 12) Detailed decision support systems to provide guidance for managing for adapt
models for Montana that account for changes in both climate and resulting vegetation distribution and patterns; 8)
Models that account for interactions and feedbacks in climate - related impacts to forests (e.g., changes in mortality from both direct increases in warming and increased fire risk as a result of warming); 9) Systems thinking and modeling regarding climate effects on understory vegetation and interactions with forest trees; 10) Discussion of climate effects on urban forests and impacts to cityscapes and livability; 11) Monitoring and time - series data to inform adaptive management efforts (i.e., to determine outcome of a management action and, based on that outcome, chart future course of action); 12) Detailed decision support systems to provide guidance for managing for adapt
Models that account for interactions and feedbacks in climate - related impacts to forests (e.g., changes in mortality from both direct increases in warming and increased fire risk as a result of warming); 9) Systems thinking and
modeling regarding climate effects on understory vegetation and interactions with forest trees; 10) Discussion of climate effects on urban forests and impacts to cityscapes and livability; 11) Monitoring and time - series
data to inform adaptive management efforts (i.e., to determine outcome of a management action and, based on that outcome, chart future course of action); 12) Detailed decision
support systems to provide guidance for managing for adaptation.
(6) Based on what is known about the behavior of the antibody and the available pharmacokinetic
data, Prothena CEO Gene Kinney has stated (albeit without presenting
modeling to
support the assertion) that «we would expect to fully saturate that pathological load [of aggregated AS] in patients with Parkinson's disease.»
Each uses a different approach to targeting these malformed proteins, and is
supported by
data in animal
models — and the early human evidence looks favorable, if very preliminary.
WMAP's
data support the big bang and inflation
models.
Professors will be trained, receive a curricular
model and be offered the ongoing technical
support required to teach undergraduate courses in Biomedical Big
Data science.
The Center
supports the development of new tools for integrating and analyzing
data from genomics, proteomics, metabolomics, molecular
modeling, and high - throughput screening, chemical biology, structural biology, and imaging, all of which involve large complex datasets that can challenge limits of available software tools and require high capacity, reliable
data storage.
The school will provide a wealth of information on good practices in the use of mouse
model (experimental design, ethics, regulations, analysis,
data and resources...) to
support attendees in their research.
Ellen Howell (National Astronomy and Ionospheric Centre, NAIC, Arecibo Observatory) and Mikko Kaasalainen (Helsinki University) were provided with photometric
data to
support radar observations and asteroid shape
modeling respectively.
The ARM
Data Center offers computing infrastructure to support next - generation ARM model simulations, petascale data storage, and big - data analytics for atmospheric and climate science resea
Data Center offers computing infrastructure to
support next - generation ARM
model simulations, petascale
data storage, and big - data analytics for atmospheric and climate science resea
data storage, and big -
data analytics for atmospheric and climate science resea
data analytics for atmospheric and climate science research.
South African Astronomical Observatory — A list of Virtual Observatory - compatible applications, tools and
data archives to do science — online data archives, data discovery, analysis, and plotting tools Mitaka 4 - dimensional digital universe — Software to visualize the known Universe with up - to - date observational data and theoretical models, by National Astronomical Observatory of Japan (NAOJ)[With Mutiple Language Support] SAO / NASA Astrophysics Data System (ADS)-- A Digital Library portal for researchers in Astronomy and Physics Virtual Astronomical Observatory (VAO)-- electronic integration of astronomy data, tools, and services to the global community SkyView — A Virtual Observatory on the Net generating images of any part of the sky at wavelengths in all regimes from Radio to Gamma -
data archives to do science — online
data archives, data discovery, analysis, and plotting tools Mitaka 4 - dimensional digital universe — Software to visualize the known Universe with up - to - date observational data and theoretical models, by National Astronomical Observatory of Japan (NAOJ)[With Mutiple Language Support] SAO / NASA Astrophysics Data System (ADS)-- A Digital Library portal for researchers in Astronomy and Physics Virtual Astronomical Observatory (VAO)-- electronic integration of astronomy data, tools, and services to the global community SkyView — A Virtual Observatory on the Net generating images of any part of the sky at wavelengths in all regimes from Radio to Gamma -
data archives,
data discovery, analysis, and plotting tools Mitaka 4 - dimensional digital universe — Software to visualize the known Universe with up - to - date observational data and theoretical models, by National Astronomical Observatory of Japan (NAOJ)[With Mutiple Language Support] SAO / NASA Astrophysics Data System (ADS)-- A Digital Library portal for researchers in Astronomy and Physics Virtual Astronomical Observatory (VAO)-- electronic integration of astronomy data, tools, and services to the global community SkyView — A Virtual Observatory on the Net generating images of any part of the sky at wavelengths in all regimes from Radio to Gamma -
data discovery, analysis, and plotting tools Mitaka 4 - dimensional digital universe — Software to visualize the known Universe with up - to - date observational
data and theoretical models, by National Astronomical Observatory of Japan (NAOJ)[With Mutiple Language Support] SAO / NASA Astrophysics Data System (ADS)-- A Digital Library portal for researchers in Astronomy and Physics Virtual Astronomical Observatory (VAO)-- electronic integration of astronomy data, tools, and services to the global community SkyView — A Virtual Observatory on the Net generating images of any part of the sky at wavelengths in all regimes from Radio to Gamma -
data and theoretical
models, by National Astronomical Observatory of Japan (NAOJ)[With Mutiple Language
Support] SAO / NASA Astrophysics
Data System (ADS)-- A Digital Library portal for researchers in Astronomy and Physics Virtual Astronomical Observatory (VAO)-- electronic integration of astronomy data, tools, and services to the global community SkyView — A Virtual Observatory on the Net generating images of any part of the sky at wavelengths in all regimes from Radio to Gamma -
Data System (ADS)-- A Digital Library portal for researchers in Astronomy and Physics Virtual Astronomical Observatory (VAO)-- electronic integration of astronomy
data, tools, and services to the global community SkyView — A Virtual Observatory on the Net generating images of any part of the sky at wavelengths in all regimes from Radio to Gamma -
data, tools, and services to the global community SkyView — A Virtual Observatory on the Net generating images of any part of the sky at wavelengths in all regimes from Radio to Gamma - Ray.
«We expected that there would be different regulatory mechanisms between the two gene types, but it's amazing how well the
data support this tuning
model,» said Berman.
These
data suggest that amylin acts on the pathological cascade in animal
models of AD, and further
supports the therapeutic potential of amylin - type peptides for AD.
Then we can fit
models to the
data, giving us a rigorous statistical assessment of whether the expression pattern we observed
supports the study hypothesis.
By
modeling metadata fields into an ontology - based semantic framework and reusing existing ontologies and minimum information checklists, the application standard can be extended to
support additional project - specific
data fields and integrated with other
data represented with comparable standards.