Sentences with word «dauer»
Methylation of the sterol nucleus by STRM - 1 regulates dauer larva formation in Caenorhabditis elegans.
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First, we find that microRNA activity is modulated during dauer in order to regulate cell fate.
The Drosophila melanogaster gene insulin - like receptor (InR) is homologous to mammalian insulin receptors as well as to Caenorhabditis elegans daf - 2, a signal transducer regulating worm dauer formation and adult longevity.
Various genes, including one called daf - 2, were known to influence dauer formation.
Metabolomics showed that chronic fatigue syndrome is a highly concerted hypometabolic response to environmental stress that traces to mitochondria and was similar to the classically studied developmental state of dauer.
When young C. elegans larvae are cultured in adverse environmental conditions, they pause their development by entering dauer quiescence — an arrested, non-aging and stress - resistant stage.
Current projects are probing the intersection of these players with developmental pathways in two cell types in C. elegans dauer larvae.
Therefore, progenitor cells in wild - type dauer larvae maintain their ability to give rise to all proper cell types.
The maintenance of multipotency during dauer is an active process involving at least two molecular mechanisms.
If conditions improve, dauer larvae recover and complete development normally.
A worm's ability to enter a «dauer» state, which resembles hibernation, may be critical, for example.
But C. elegans can enter a dormant «dauer» stage, which enables the worm to survive long periods of adverse conditions, so some people had thought that genetic control of aging might only occur in worms.
Among other things, Ruvkun's group scrutinized a hibernation phase in the C. elegans life cycle — the dauer larval stage — in which the nematode stops growing under unfavorable conditions.
Suddenly and unexpectedly, Ruvkun's dauers were leading him into the study of aging.
Second, we find that DAF - 16, the FOXO ortholog, is important for maintaining multipotency during dauer.