Sentences with word «deacetylation»
Deacetylation is the process of removing an acetyl group from a molecule. It can occur naturally in living organisms or be done in a laboratory setting. This process plays a role in various biological and chemical reactions. Full definition
However, by changing the DNA sequence of the natural form of HDAC3, the team now shows that enzyme - dead HDAC3 mutants are not able to perform histone deacetylation but are still able to repress gene expression and substitute for natural HDAC3 in preventing fatty liver.
sciencedaily.com
Chitosan is naturally or synthetically produced by deacetylation of chitin (removing acetyl [COCH3] groups).
SIRT1 deacetylation by the NAD + salvage pathway may regulate the cellular redox system, the energetic process underlay ROS production.
PARP family members are also NAD + - consuming enzymes which degrades NAD + in NAM and O - acetyl ADP ribose by sirtuin mediated deacetylation.
This form may induce extension lifespan mediated by sirtuin activity in deacetylation - indipendent manner.
Discovered that the activation of sirtuins — class III histone deacetylases strongly associated with longevity — protects neurons by block NF - κB activation in microglia through deacetylation.
Valproic acid reduces histone deacetylation, in effect promoting acetylation, as the oncogene does.
Showed that acetylation / deacetylation of RelA subunit of NF - κB functions as an intranuclear switch controlling both the magnitude and duration of its transcriptional response.
I had to quickly pick up on words like «orthodromic» and «deacetylation» to communicate with my peers.
From this, the researchers concluded that deacetylation must be the underlying chemical reaction leading to suppression of the plant's immune response.