Studies suggest that stem cells sustain
deadly tumors in the brain — and that aiming at these insidious culprits could lead to a cure
Not exact matches
When she was 18, still
in high school, Chantelle was found to have an absurdly rare and
deadly tumor.
Northwestern Medicine scientists have identified a small RNA molecule called miR - 182 that can suppress cancer - causing genes
in mice with glioblastoma mulitforme (GBM), a
deadly and incurable type of brain
tumor.
SURVIVAL GEAR Some genetic variants may have allowed a small number of Tasmanian devils to withstand a
deadly contagious facial
tumor that has killed up to 95 percent of them
in some locales.
Engineered human immune cells can vanquish a
deadly pediatric brain
tumor in a mouse model, a study from the Stanford University School of Medicine has demonstrated.
Because cancer that comes back and spreads after initial treatment is often
deadlier than the original
tumors, researchers thought most of the mutations
in recurrent
tumors happened after they spread.
Baliga's group is also mapping networks
in patients with glioblastoma, a particularly
deadly type of brain
tumor.
DIPG is the most
deadly brain
tumor in children and currently there are no approved drugs for treating it.
«Pancreatic cancer cells are
deadly because they program nearby immune cells to permit the
tumors to survive and grow,» says study author George Miller, MD, head of the Cancer Immunology Program at Perlmutter and vice chair for research
in the Department of Surgery at NYU Langone.
Immunotherapy, the hottest field
in cancer research, seeks to supercharge the body's natural defenses against
deadly tumors.
The method could potentially,
in the future, offer clinicians going after individual
tumors a weapon to combat cancer's
deadly spread at the same time.
For years, bioengineer Yaling Liu has been
in pursuit of the
deadly tumor cell.
The study, which appears August 3
in the peer - reviewed journal Nature Communications, showed that pairing the chemotherapy with an experimental drug eliminates the
deadly population of cells believed to be responsible for repopulating the
tumor.
Genetically modified «hunter» T cells successfully migrated to and penetrated a
deadly type of brain
tumor known as glioblastoma (GBM)
in a clinical trial of the new therapy, but the cells triggered an immunosuppressive
tumor microenvironment and faced a complex mutational landscape that will need to be overcome to better treat this aggressive cancer, Penn Medicine researchers report
in a new study this week
in Science Translational Medicine.
Deadly brain
tumors called high - grade gliomas grow with the help of nerve activity
in the cerebral cortex, according to a new study by researchers at the Stanford University School of Medicine.
«Novel imaging model helps reveal new therapeutic target for pancreatic cancer: Antisense treatment
in preclinical models shows effectiveness against
deadly tumors.»
The Cosford lab employs medicinal chemistry and chemical biology approaches to probe cellular pathways that regulate cell survival pathways
in deadly tumors.
Our researchers have identified a bacterial - based therapy for attacking pancreatic
tumors, offering hope
in the fight against one of the
deadliest cancers.
In these
deadly dispersed
tumors, Trotman and his colleagues were surprised to find that a different cancer gene, called Myc, had taken over.
A viral culprit suspected to be responsible for the disfiguring and potentially
deadly tumors that affect many persons with AIDS is now
in hand, scientists at the Howard Hughes Medical Institute -LRB-...
Brain
tumors are a particularly
deadly form of cancer, and the leading cause of cancer - related death
in children.
As a
tumor immunologist at UCLA's Jonsson Comprehensive Cancer Center, Dr. Ribas specializes
in the research and treatment of melanoma, the
deadliest form of skin cancer.
«This clinical trial targets glioblastoma — one of the
deadliest forms of brain
tumor,» said principal investigator Santosh Kesari, MD, PhD, director of neuro - oncology
in the Moores Cancer Center and
in the Department of Neurosciences at the University of California, San Diego.
Knocking out or blocking the activity of Nrp1 on regulatory T cells
in mouse models of several human cancers, including the
deadly skin cancer melanoma, led to reduced, delayed or complete elimination of the
tumors.
This finding suggests that high cellular cholesterol content could push immune cells like macrophages into
tumor - fighting mode and presents a very intriguing paradox: namely that inflammation that is
deadly in the context of atherosclerosis may be beneficial when it comes to cancer.
Sadly, this lovely breed suffers from malignant
tumors of all kinds — most notably
deadly histiocytic sarcoma, which occurs
in Flat - Coated Retrievers and Bernese Mountain Dogs FAR more than
in any other breed.
Skin lumps, which are common
in dogs, can be noncancerous or a
deadly tumor.
RESULTS: Researchers identify a chemotherapy resistance mechanism
in hemangiosarcoma
tumor cells Hemangiosarcoma is a common and
deadly tumor of dogs.