Sentences with phrase «deamination of»
Based on the nucleotide context, the authors suggest that a new mutational mechanism may be at work involving cytosine deamination of single - stranded DNA (presumably during replication).
http://massgenomics.org/
The SureSeq mix increases the success and accuracy of hybridization - based NGS for FFPE samples by repairing damage such as nicks and gaps, oxidized bases, blocked 3» ends, and deamination of cytosine to uracil.
Not exact matches
The recovered DNA sequences exhibited signatures of postmortem DNA damage typical of ancient DNA, with preferential fragmentation at purines and inflated rates of cytosine deamination at single - stranded overhangs (19, 20).