Sentences with phrase «death of neurons»

The paralysis is caused by the gradual death of the neurons that control movement.

Various studies carried out in previous years showed that the binding of GDNF to its Ret receptor can prevent the early death of neurons in the Substantia nigra.

Calcium plays a crucial role in cell death, she said, and high levels of calcium in the blood might prompt the early death of neurons.

The peracute spinal cord injury with IVDD is related to compression of the spinal cord and death of neurons with secondary inflammation.

The symptoms of Parkinson's — which is characterized by stiffness and can lead to a loss of motor and speech function — are triggered by the progressive death of neurons in a midbrain region called the substantia nigra that produce the neurotransmitter dopamine (implicated in the pleasure and reward systems as well as in the maintenance of proper movement control).

Researchers believe that this inhibitory process caused by an overabundance of alpha - synuclein is what occurs in the early stages of Parkinson's disease, before morphological changes such as the loss of function and death of neurons begins.

Using a unique, automated robotic microscope that can follow a single cell over days or weeks, the scientists track the birth, maturation, and death of neurons afflicted with Alzheimer's, Huntington's, and Parkinson's diseases and ALS.

A team at Northwestern University's Feinberg School of Medicine in Chicago reports that isradipine (brand name DynaCirc), a drug currently prescribed to reduce high blood pressure, may block the death of neurons in patients with advanced cases of Parkinson's and may also be able to prevent the development of the disease.

The movement disorder stems from the death of neurons that produce dopamine, a neurochemical that dispatches messages to parts of the brain that control motor skills and coordination.

Indrani Das of Oradell, N.J., won the top award for her study of a possible approach to treating the death of neurons due to brain injury or neurodegenerative disease.

Neurodegenerative diseases are caused by the death of neurons and other cells in the brain, with different diseases affecting different regions of the brain.

Parkinson's disease is caused by the death of neurons in the brain that produce dopamine, a chemical that shuttles signals between neurons and is responsible for controlling the body's movement.

That's because the movement problems and other symptoms of the disease are caused by the death of neurons, located in a part of the brain called the substantia nigra, that produce the neurotransmitter dopamine.

Acetaminophen can cross the placental barrier, Ritz noted, and it is plausible that acetaminophen may interrupt fetal brain development by interfering with maternal hormones or through neurotoxicity, such as the induction of oxidative stress, which can cause the death of neurons.

This study may provide insight for treatments that would be effective in slowing down or postponing the death of neurons for people who carry the HD gene mutation, but who do not yet show symptoms of the disease.

Several years ago, in tissue culture studies of mouse neurons, Dr. Shelanski found that caspace - 2 plays a critical role in the death of neurons in the presence of amyloid beta, the protein that accumulates in the neurons of people with Alzheimer's.

In an earlier study, Subramaniam and his colleagues showed that Rhes binds to a series of repeats in the huntingtin protein (named for its association with Huntington's disease), increasing the death of neurons.

The findings may provide insight into treatments that could postpone the death of neurons in people who carry the HD gene mutation, but who do not yet show symptoms of the disease.

«The prevailing view in the field has been that immune system inflammation contributes to the death of neurons in ALS, but this study shows the opposite — that microglia are actually critical for neuronal survival,» Lee said.

Scientists have identified the molecular mechanism that leads to the death of neurons in amyotrophic lateral sclerosis (also known as ALS or motor neurone disease) and a common form of frontotemporal dementia.

This damages nerve cells by blocking their ability to make the proteins needed for synaptic function and leads to the death of neurons in the brain and spinal cord.

This leads to the death of neurons, which stops them from communicating with each other and from reaching the muscles.

Researchers have discovered how the abnormal repetition of a genetic sequence can have disastrous consequences that lead to the death of neurons that govern balance and motor coordination.

They all result in the death of neurons, but the cells that die are somewhat different in each case.

As organisms age, the function of neurons becomes compromised and this often results in the death of neurons (or neurodegeneration).

When studying neurodegenerative diseases such as Parkinson's, which are defined by the degradation and death of neurons, traditional tools usually only allow researchers to track neuronal death at the population level.

Brain Basics: The Life and Death of a Neuron.

These losses are related to the death of neurons in the brain.

This cognitive decline is not only due to the death of neurons, but also during aging there is a loss of neuronal connections called... >> MORE

The findings raise the possibility that the death of neurons in Parkinson's could be prevented by therapies that dampen the immune response.

This cognitive decline is not only due to the death of neurons, but also during aging there is a loss of neuronal connections called synapses, as well as a decline in function of the remaining synapses.

Excitotoxins interfere with normal brain function by overstimulating neuron receptors in the hypothalamus and causing the death of neurons.