Sentences with phrase «death of the cell»

This can cause cell mutation or even death of the cell.

This allows the bacteria normally held in check within the intestine to flourish, resulting in death of the cells in the lining and subsequent shutting down of the intestinal tract.

These pathologies fall broadly into four categories: coagulopathy, where abnormal blood clotting is caused; haemorrhaging, where bleeding occurs; neurotoxicity, which damages the nervous system causing paralysis, and cytotoxicity, where the bite causes death of cells and destruction of tissue.

«Our study results are the first to argue that we may be able to treat inflammatory bowel disease and protect against transplant rejection not only by blocking TNF alpha as is done currently, but also by stimulating ATG16L1 to prevent early death of cells lining the gut,» says study senior investigator Ken Cadwell, PhD, an associate professor at NYU School of Medicine and NYU Langone Health's Skirball Institute for Biomolecular Medicine.

AMD, a major cause of irreversible vision loss in the elderly, results from death of cells critical for vision: RPE and photoreceptor cells.

We have found that modifying the response of the sclera to IOP changes can prevent death of the cells that cause vision loss in glaucoma — retinal ganglion cells (RGCs).

Roughly 2 % of people over age 35 have chronic glaucoma, in which fluid builds up inside the eyeball, leading to increased pressure and eventual death of cells in the optic nerve.

Then, in the presence of TB drugs, that increased respiration will lead to rapid death of the cells.

Paligenosis, Mills explains, appears similar to apoptosis — the programmed death of cells as a normal part of an organism's growth and development — in that it seems to happen the same way in every cell, regardless of its location in the body.

Specifically, this study looked at the HL - 60 cells and found that hibiscus tea could cause cancer cell apoptosis, which means death of the cells.

Necrosis is literally the «premature death of cells and living tissue.»

Once telomeres reach a critically short length, cell renewal virtually stops, leading to accelerated aging or death of the cell.13

Previous studies of this type relied on microscopic examination of tissue samples from sacrificed animals, but this new approach allows researchers to watch the life or death of cells in real time.

Specifically, HIV targets T helper cells (CD4 cells), leading to the eventual death of the cell.

«Imagine if we could create circuits that detect defects in cancer cells and then turn on pathways that lead to the death of those cells,» he says.

Death of these cells in the PPN is believed to be the cause of some of the symptoms of Parkinson's disease, such as problems with attention, walking and posture.

The researchers identified a genetic mutation in the tumor cells that plays a role in both the growth and the death of a cell.

The drug that Romesberg was looking at in this case was Cipro, the drug that was made famous during the anthrax scare, and Cipro has to bind to a particular protein that causes damage to the DNA and ultimately results in death of the cell.

Even without these agents, a combination of drugs can also induce the death of cells in the early cellular stage of spermatogenesis (spermatogonia) with a higher toxicity than either component alone.

When scientists gave mice an oral drug called LM11A - 31 (designed to prevent neural degeneration in Alzheimer's patients) just hours after a complete spinal cord injury, it limited the death of cells that protect nerve fibers, allowing test rodents to retain their ability to walk and swim.

These factors promote cell growth in the brain and prevent the death of cells in the hippocampus which is otherwise caused by depression.

The proposed manipulation system makes it possible to place cells in a microwell array and observe the adherence, spreading, culture, and death of the cells.

Further, they have identified an existing anti-inflammatory drug that in laboratory tests blocks the death of these cells — and now are planning a Phase 2 clinical trial to determine if this drug or a similar drug can prevent HIV - infected people from developing AIDS and related conditions.

In their experiments, mice with two copies of the recessive Gatm mutation showed symptoms similar to people with IBD: diarrhea, weight loss, and the death of cells lining the intestine.

The flu vaccine is designed to trigger antibodies to influenza's surface proteins, but if it elicits antibodies to the nucleoprotein as well, those might well latch on to the hypocretin receptor, and eventually lead to death of the cells, the researchers thought.

Loss of sight in patients with glaucoma is caused by the death of cells in the retina at the back of the eye.

This ultimately leads to death of the cell.

They observed that the fly was born alive but without wings; so the removal of this molecule caused the death of all cell precursors of this tissue (if histone 1 is removed from the entire fly, the embryo dies).

It results from the death of cells critical for vision: retinal pigment epithelial cells (RPE) and photoreceptor cells.

Keynote presenter Mark Gillespie, PhD Chair of Pharmacology at the University of South Alabama presented Oxidant - DNA interaction in the life and death of cells: A tale of two genomes.

A group of scientists led by Aaron Gitler at the University of Pennsylvania set out to discover what genetic factors influence the death of cells in ALS.

Deletion of an essential gene from a cell eventually leads to the death of this cell or a severe proliferation defect.

On the surface, the disease appears relatively simple, with high pressure (intra-ocular pressure, or IOP) within the eye associated with the death of cells in the retina and optic nerve dysfunction.

Dr. Salvesen's research focuses on the central role enzyme pathways play in the life and death of cells.

For 50 years of brilliant creativity in biomedical science — exemplified by his legendary work on the genetic code; his daring introduction of the roundworm Caenorhabditis elegans as a system for tracing the birth and death of every cell in a living animal; his rational voice in the debate on recombinant DNA; and his trenchant wit.

High blood levels of creatinine almost always suggest a kidney disease, most often including damaged blood vessels, infections or death of cells caused by toxins.

There is a resulting buildup of lactic acid, which leads to pain and death of the cells.

As part of the process of creating energy, they can also create free radicals that damage the DNA of mitochondria and result in the death of the cell.

Because progesterone promotes the healthy growth and death of cells, the hormone does two things.

Myocardial infarction refers to death of the cells in an area of the heart muscle or myocardium.

Although enteritis is the most common sign of Parvo, severe inflammation of the muscles in the heart and the death of cells (called necrosis) can also cause difficulty of breathing and death in puppies less than eight weeks old.

DJD, also called osteoarthritis, causes a progressive loss of cartilage and the death of cells that produce cartilage in both humans and dogs.

The drug within the tumor is activated by a specific wavelength of light to generate intracellular oxygen and lead to death of cells and / or loss of blood supply.

Since the stomach can not drain, it becomes distended, interfering with circulation in the stomach and the death of cells in the wall of the stomach (called necrosis).

The disease results from the death of cells in a particular region of the midbrain, known as the basal ganglia, as well as a deficiency of dopamine, a neurotransmitter.