Sentences with phrase «death signalling in»

One way that curcumin inhibits cancer is by restoring normal cell - death signalling in a cancerous cell.

From zero to sixty: cell death signaling in the city that never sleeps.

Insulin - like growth factor - I blocks Bcl - 2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons.

Interestingly, fluid shear stress also modulates how tumor cells respond to apoptosis death signals in the bloodstream.

Not exact matches

In France, this resulted in the passage of the highly protectionist Méline Tariff of 1892, which famously signaled the death knell of the country's flirtation with free tradIn France, this resulted in the passage of the highly protectionist Méline Tariff of 1892, which famously signaled the death knell of the country's flirtation with free tradin the passage of the highly protectionist Méline Tariff of 1892, which famously signaled the death knell of the country's flirtation with free trade.

November 3, 2017 — When President Donald Trump pulled the U.S. out of the Trans - Pacific Partnership in the days following his inauguration, many thought it would signal the death of, what was at the time, the globe's largest trade pact.

However, I do not believe that it could not possibly survive the death of the body because it is embodied in the unique patterns of electrical and chemical signals in the brain.

The motive was the public rendering of thanksgiving / praise to God by the person commissioning the ritual in the presence of relatives and friends for God's signal intervention in saving the man (and his family, if the occasion called forit) from death in war or in some similar grave danger such as famine.

If charities allow themselves to be used as «extra civil servants» by governments, they will signal the death of their organizations, resulting in an unfortunate loss for many communities.

Christian congregations in particular have skyrocketed since churches began reopening when Chairman Mao's death in 1976 signalled the end of the Cultural Revolution.

According to Peter Berger, moral outrage in the face of evil, courage in defiance of death, and trust in an underlying cosmic order are among the «prototypical human gestures» which can be interpreted as «signals of transcendence».

Literary critic Terry Eagleton wrote in 1987: «Post-modernism signals the death of «meta - narratives».

In fact, Green's huge role for the Grizzlies in 2016 - 17 signaled the impending death of Grit»n' GrinIn fact, Green's huge role for the Grizzlies in 2016 - 17 signaled the impending death of Grit»n' Grinin 2016 - 17 signaled the impending death of Grit»n' Grind.

This can lead to unconsciousness and even death in mere minutes and often goes unnoticed because baby is in a position where he can not send out a stress signal.

Blood samples from infants who died of Sudden Infant Death Syndrome (SIDS) had high levels of serotonin, a chemical that carries signals along and between nerves, according to a study funded in part by the National Institutes of Health.

In particular, I think the attack on the Arab League peace initiative is bizarre and hopeless; I take the references to the «whole of Palestine» to again signal the refusal to recognise any status of the state of Israel; the concern to stress the illegitimacy of the Palestinan authority too suggests it is not simply Hamas but pro-traditionalist Hamas (when many observers believe there is an opportunity, with Hamas engaged in electoral politics, for it to drop the death to Israel position of its founding charterIn particular, I think the attack on the Arab League peace initiative is bizarre and hopeless; I take the references to the «whole of Palestine» to again signal the refusal to recognise any status of the state of Israel; the concern to stress the illegitimacy of the Palestinan authority too suggests it is not simply Hamas but pro-traditionalist Hamas (when many observers believe there is an opportunity, with Hamas engaged in electoral politics, for it to drop the death to Israel position of its founding charterin electoral politics, for it to drop the death to Israel position of its founding charter).

James praised the vote in a statement, saying it signals «that we will no longer do business with companies that fund the deaths of our family members and friends.»

In the wake of 12 - year - old Dashane Santana's death last month, the Department of Transportation plans to widen sidewalks into landscaped plazas and change traffic patterns and signal timing along the most dangerous stretches of Delancey Street, officials told Community Board 3.

When Hong further boosted MAPK signals and DNA damage in the tumor cells, she found that she could intensify tumor cell death.

For some years now, a new class of drugs called antibody - drug conjugates (ADCs) have been used, which work in two ways: they consist of an antibody that binds selectively to the tumor cell receptor and interrupts the signal to propagate; they also act as a transport vehicle for a chemical substance that enters the cancer cells with the antibody and triggers their death.

Parkinson's disease is caused by the death of neurons in the brain that produce dopamine, a chemical that shuttles signals between neurons and is responsible for controlling the body's movement.

The new chimera interferes with HER2 and HER3 signaling and ultimately leads to cancer cell death, as shown in the group's recent publication in Molecular Therapy: Nucleic Acids.

Previous studies identified three sub-events at intervals of 20 seconds in the seismic signals recorded during the 1980 Irpinia earthquake sequence, whose shared ground motion caused more than 3000 deaths and significant damage to structures.

(In contrast, cancer cells fail to respond to the environmental signals that regulate cell death.

It can sense the presence of DNA damage, signal to other proteins that damage exists, aid in the repair of damage and stimulate cell death if the damage can not be repaired.

Both discoveries came from studies of mitochondria, the powerhouses of the cell that burn nutrients for energy but also play a key role in signaling, cell death and growth.

Blood samples from infants who died of Sudden Infant Death Syndrome (SIDS) had high levels of serotonin, a chemical that carries signals along and between nerves, according to a study funded in part by the National Institutes of Health.

In addition to rendering lungs unusable for transplant, pulmonary edema also signals that the lungs are not functioning properly post-transplant and is a major cause of illness and death among lung transplant recipients.

As described in Nature, pyroptosis ensues as immune cells rupture and release inflammatory signals that attract still more cells to repeat the death cycle.

In most nerve agent fatalities, death occurs after the agent binds to enough AChE to block signal transmission from the brain's respiratory center to the diaphragm, paralyzing the muscle that's vital for breathing.

In fact, researchers at Stanford are already collaborating on initial clinical trials of an antibody that blocks cancer cells from displaying one such death - evading signal — a molecule called CD47.

«We're excited to be contributing to a growing area of study of how astrocytes contribute to neurodegeneration, and to have uncovered a role for NO as a neuronal cell death signaling molecule,» said corresponding author Mel B. Feany, MD, PhD, a senior pathologist in the BWH Department of Pathology.

The researchers injured the mice retinas with a toxin that causes cell death in retinal ganglion cells and interneurons, another type of retinal cell whose job it is to transmit signals from photoreceptors to the brain.

Retinal cell death can be induced by phagocytic immune cells that infiltrate the tissue in response to injury or infection, but the molecular signals that trigger phagocyte invasion are largely unknown.

The team led by Rory Fisher, Ph.D., professor of pharmacology in the UI Carver College of Medicine, has identified a protein called RGS6 (regulator of G protein signaling 6) that acts through two separate mechanisms to control alcohol - seeking behavior and alcohol - induced cell death in heart, liver, and other organs.

Werlen, G., Hausmann, B., Naeher, D. & Palmer, E. Signaling life and death in the thymus: timing is everything.

In this artist's rendering, jets of high - energy radiation shoot out from a Gamma - ray burst, signaling the death of a massive star.

With collaborators in the biology department, Dr. Weiss applied these ultrasensitive techniques to investigate the Hedgehog signaling pathway — a critical mechanism that helps give rise to the spatial patterning in developing embryos, but has also been identified as a key culprit in up to 25 % of cancer deaths.

Protein kinase Cα and ζ differentially regulate death - inducing signaling complex formation in cigarette smoke extract - induced apoptosis.

Once inside, the virus's DNA acts as a danger signal that activates a protein called caspase 1, which can initiate cell death in several ways, including opening pores that disturb the cell's ion balance and releasing inflammatory signals that recruit other immune cells.

The signaling molecule CD95L, known as «death messenger,» causes an inflammatory process in injured tissue after spinal cord injuries and prevents its healing.

Follin - Arbelet V, Torgersen ML, Naderi EH, Misund K, Sundan A, Blomhoff HK Death of multiple myeloma cells induced by cAMP - signaling involves downregulation of Mcl - 1 via the JAK / STAT pathway Cancer Lett (in press) PubMed 23454584

In glaucoma, EDN signaling increases in retinal cells before any damage occurs, and blocking it lessens cell deatIn glaucoma, EDN signaling increases in retinal cells before any damage occurs, and blocking it lessens cell deatin retinal cells before any damage occurs, and blocking it lessens cell death.

The King Lab has pioneered the use of selectin proteins to deliver apoptosis death signals to tumor cells in flowing blood, and to deliver therapeutic cargo (e.g., siRNA, chemotherapeutics) encapsulated in nanoscale liposomes.

Tribbles normally binds and blocks the action of AKT, an insulin signaling protein directly involved in cell death and proliferation — and the tribbles genetic variants bound more strongly to AKT, thereby blocking proliferation and promoting cell death.

Death - associated protein kinase (DAPK) and signal transduction: fine - tuning of autophagy in Caenorhabditis elegans homeostasis.

By identifying, activating and inhibiting critical signaling nodes in cells, the scientists seek to better understand how these drive responses such as cell death and differentiation.

Calcitonin Gene - Related Peptide Enhances the Expression of Signaling Molecules of the Wnt 7b / Beta - Catenin Pathway in Rat Type II Alveolar Epithelial Cells Under Hyperoxia Hyperoxic lung injury is characterized by epithelial cell death and leukocyte infiltration / inflammation in the lung.

Read about the monitoring of apoptosis and necrosis in real time using the CLARIOstar's ACU feature, that maintains the appropriate O2 and CO2 environment for cells, while the RealTime - GloTM Annexin V Apoptosis and Necrosis Assay measures cell death using luminescence and fluorescent signals.

Since TNFα is such a potent inducer of apoptosis through TNFR1 death domain signaling, and amiodarone treatment results in the down regulation of TNFα with concomitant upregulation in TNFR2 signaling in NSC alone, it is possible that amiodarone selectively kills NSCs by lowering the threshold of TNFα required to trigger apoptosis in NSCs via upregulation of TNFR2 pathways in NSCs and not dopaminergic neurons.