Rats fed protein - deficient diets have
decreased DBP concentrations and a
decreased ability to regulate calcium metabolism.38 Humans with acute liver failure also have depressed levels of DBP.39 This may be because the synthesis of DBP in the liver declines during such a condition, but DBP also plays a secondary role in scavenging harmful cellular
debris from the blood; therefore, any kind of acute tissue damage can overwhelm our supply of DBP.