Women with Stage III ovarian cancer given a combination of intravenous and intraperitoneal chemotherapy following surgical
debulking of tumor had a median survival nearly 16 months longer than women who received IV chemotherapy alone, according to a study published conducted by the Gynecologic Oncology Group (GOG), a National Cancer Institute - supported research network, in the January 5, 2006 issue of the New England Journal of Medicine.
Our surgical oncologists provide the highest - quality cancer care to diagnose and remove tumors,
debulk tumors to help make chemotherapy or radiation therapy more effective, and relieve symptoms or side effects of therapies.
Platinum - sensitive ovarian cancer patients with a positive predictive AGO score who undergo a secondary
debulking surgery after relapse on platinum chemotherapy experience longer progression - free survival.
The primary role of surgery is to biopsy and ascertain the diagnosis and, in some circumstances, there's a role
for debulking or removal of a significant volume of tumor.
«So, we loaded MSCs with oncolytic herpes virus and encapsulated these cells in biocompatible gels and applied the gels directly onto the adjacent tissue
after debulking.
The study, led by Deborah Armstrong at the Johns Hopkins Kimmel Cancer Center in Baltimore, Maryland, builds upon evidence from eight other clinical trials showing an overall survival benefit of approximately one year for women treated with IP chemotherapy after «
optimal debulking» — surgery to remove most, if not all, of the cancer in the abdomen.
Despite hematologic toxicities and port - related adverse events, IP carboplatin plus IV dose - dense paclitaxel appears to be effective in patients with
suboptimally debulked epithelial ovarian or primary peritoneal carcinoma.
I only recommend surgery if one has a good chance of removing or at least
significantly debulking enough of the tumor to improve quality of life and perhaps enable an adjunctive therapy to work better then.
Using a cystoscope and diode laser, we can
often debulk / relieve obstruction caused by these tumors, possibly allowing additional time for chemotherapy to take effect.
Treatment
requires debulking and adjuvant cryosurgery or full - thickness eyelid resection.
Treatment of malignant glioma using gene transfer modalities typically consists of
surgical debulking of the tumor mass followed by the administration of the viral vectors into the brain tissue surrounding the tumor cavity.
Surgery is generally used as an emergency, palliative process
for debulking (removal of excess bulk of tissue from a lesion), inoperable tumors in dogs with distal urinary tract obstruction.
It can be used alone or in combination with surgical
debulking of a tumor and then follow up with neoplasene topical and / or oral.
«We know that 70 - 75 percent of glioblastoma patients undergo surgery for tumor
debulking, and we have previously shown that MSCs encapsulated in biocompatible gels can be used as therapeutic agents in a mouse model that mimics this debulking,» he continued.
Using imaging proteins to watch in real time how the virus combated the cancer, Shah's team noticed that the gel kept the stem cells alive longer, which allowed the virus to replicate and kill any residual cancer cells that were not cut out during
the debulking surgery.
We then compared the efficacy of virus - loaded, encapsulated MSCs versus direct injection of the virus into the cavity of
the debulked tumors.»
Unlike other solid tumors, RCC is unique in
that debulking nephrectomy has been the mainstay of therapy even in the setting of metastatic disease.
As a side note, if your surgeon wants to «
debulk» your colon and / or stomach of cancer cells and tumors, keep this in mind: colon cancer and stomach cancer patients have a lower cure rate than other cancer patients precisely because surgery and chemotherapy damages the ability of their stomach and colon to properly digest foods.
If your surgeon wants to «
debulk» your colon and / or stomach of cancer cells and tumors, keep this in mind: Colon cancer and stomach cancer patients have a lower cure rate than other cancer patients precisely because surgery and chemotherapy damage the ability of their stomach and colon to properly digest foods.
Do you recommend doing only LISS for an hour, 5 times a week until
I debulk my frame, or should I do less cardio and incorporate strength training, or body weight workouts?
It still may be the best approach to do the s surgery and «
debulk» the amount of insulinoma.
Since this cancer frequently involves an area of the bladder known as the trigone (where the ureters and urethra empty urine into the bladder), surgical
debulking may not be possible.
But most of these tumors can be surgically removed (
debulked) and the dog or cat then treated with radiation.
If obstruction of the urinary tract occurs, catheterization, definitive anti-cancer therapy and antibiotics to reduce inflammation associated with secondary bacterial infection or surgical
debulking are recommended.
Debulking is surgery to reduce a large tumor so that chemotherapy or radiation therapy has a better chance of working.
Another surgical technique frequently used is
debulking.