Sentences with phrase «decades of failures in»

Despite decades of failures in Alzheimer's drug development, scientific attention continues to focus on drugs that «attack» a molecular compound called beta amyloid, with the goal of curing the disease.

Superintendent Cami Anderson is answering decades of failure in Newark with an ambition and urgency that's long overdue.

Not exact matches

«Under - emphasis of these (structural) policies relative to macroeconomic, trade and financial stability policies is a key reason for many governments» failure in recent decades to mobilize a more effective response to widening inequality and stagnating median income as technological change and globalization have gathered force,» the report said.

For starters, there were certain operational failures, some of which — like menu creep — had been decades in the making.

The failure of coalition talks is unprecedented in Germany's post-war history, and was likened by newsmagazine Der Spiegel to the shock election of U.S. President Donald Trump or Britain's referendum vote to leave the EU - moments when countries cast aside reputations for stability built up over decades.

Early in the decade the company had been dogged by R&D failures, most notably of Vanlev, a high - profile hypertension drug that had been hailed as a can't - miss blockbuster but then fell short of even getting FDA approval.

Despite Vogel's involvement in the case that took away 18 years of Avery's life, the attorney does not seem to be experiencing the same level of backlash as Kratz (perhaps because the state's failures in 1985 have been well known to the public for more than a decade at this point).

«The takeaway from it is that even though the technology is getting better and pipeline companies are spending a lot more money on inspecting pipelines, there's been an uptick in failures over the last decade,» said Carl Weimer, executive director of the Pipeline Safety Trust, a Bellingham, Washington - based watchdog group.

It will always be uncomfortable to watch hopes, dreams and hard work end up in failure, but the alternative is even worse: tax - payer support of European & (especially) Japanese banks that «extend & pretend» with years, decades of bad loans to zombie companies, and no capital to lend to new, vibrant companies.

These are helpful.You are right that market failures have hit elder popluation in heavy way in past decade or so, and on top of that the fed locks interest at artificial rate low, so if we did save like our wise elder and financial advisors told us to do, we now get about nothing at all in interest return on those life savings.

Meanwhile, many of the old dot - com failures — including the most comical ones — were reanimated as successes in the decades that followed.

It speaks to an incredible failure of Wall Street to learn from its mistakes (or at least the mistakes that it foists onto unsuspecting investors), and the likelihood of making nearly the same mistake for a third time in just over a decade.

The Guardian: Bishop's arrest part of broad inquiry into Chichester diocese child abuse The arrest of Bishop Peter Ball on suspicion of sexual offences against boys and men at addresses in East Sussex and elsewhere is the latest development in a wide - ranging and often contentious series of official inquiries into decades of alleged child protection failures in the diocese of Chichester on England's south coast.

The problem is that generally the fans who want Wenger out, (not all of them though) see the last decade as a failure, but forget that from 2005 - 2012, we had limited funds to compete with and unfairly throwing in that period with the last 2 years and calling it a failure.

Sadly after more than a lost decade of the frenchman's bs and failure to deliver more than 4th place expectations sarcasm no longer has a place in arsenal fc

the obvious fact is that the club began to stagnate in football terms a decade ago after the CL semi against man utd and has been in outright retreat over the last 3 years... some fans were calling for wenger to leave in 2011 - 12 as it was clear he could not cope with a more competitive environment others have been more tolerant, hanging on to fa cup glory and hoping that he would somehow self correct his weak and erratic management style but most now realise that is not possible and that the club will deteriorate further under his management so also want him gone, that has left a hard core of wenger loyalists who are either fixated with the past (selecting episodic good and bad times to justify wengers decade long failure) or too frightened of the future to contemplate a change (with selective reference to failed managerial changes by way of justification) or both, to conclude, through a mixture of panglossian fatalism and corporate philosophising, how lucky we are to have such an honourable and educated man in charge... along with their confused references to club loyalty and addiction to computer games these are troubled souls who need our sympathy and concerned medical advice... SO JUST F OFF STOCK UP ON CANNED SOUP AND GO SUPPORT ASTON VILLA ON FIFA!

lpool will benefit from the klop factor and chelski will eventually crawl their way back to somewhere near contention for 4th place... this is the weakest EPL i can remember and we are in our usual position... to me that adds up to a decade of football failure from the complaining one... hope for the best but prepare for a difficult winter

Until the fans forcefully take the club back, the usual continues: Arsene's legacy of loving failure and excuses, arsenal being brilliant for some weeks and losing decisive games at crucial time, a good run at fa cup, injuries more than any other top club, AKBs declaring total support for brilliant Wenger, the American animal torturer giving prof contract extension, Usmanov making weak attempts at takeover, Dangote forever promising to buy us out; and in that time, all the major clubs each clinch a prem title again, even spud having a taste, while for almost two decades we have been dreaming under Arsene's sedatives!

We're talking about a decade of failure, lies, and the fact we're arguably the worst treated football fans by their respective club, in Europe, maybe even the whole world!

the wenger out brigade just goes for the prof because he epitomises the failures arsenal has had in the past decade, yes managerial failures name the youth products that are world class since 2007, a proper trophy, a tactical innovation, a unique way of training??? I respect him and believe he's a legend at this club, I'm just gutted to see him go like this he should have went on a high and got replaced, I'm sure the same fans that say wenger out would love a statue of him at the emirates.

Two guys that we hope don't continue the half decade tradition of miserable failure in the Secondary.

Wenger has had numerous periods of success and failure in his two decades in England, creating a few fierce rivalries along the way.

Objections to a HIQA review echo past failures in transparency and a lack of accountability which have plagued the Irish maternity services for decades.

In particular, a massive overhang of debt from a decade - long boom when economic growth was based on unsustainable household borrowing, unrealistic house prices, dangerously high banking leverage, and a failure of governments to put their public finances in ordeIn particular, a massive overhang of debt from a decade - long boom when economic growth was based on unsustainable household borrowing, unrealistic house prices, dangerously high banking leverage, and a failure of governments to put their public finances in ordein order.

The Thatcherite Right (and the Bennite Left) in the early 1980s saw the 1970s as a «lost decade» and a «decade of failure».

On Board Diagnostics (OBD)- will be compulsory in two stages OBD 1 and 2 Myth busting reality: Not an onboard tracking device — only shows component failure or component out of tolerance Will not stop bike working Emissions - Bring pollutant limits for bikes in line with cars in three stages over the next decade.

Although the policy has been covert, the failure to accommodate extra traffic has been an effective and successful deterrent to growth of car use, which indeed has barely increased in the past decade.

Top of their list is a schools chief who can help distance their new administration from the perceived failures of Bloomberg's decade in charge, but one with strong insight into how the Department of Education works, insiders told DNAinfo New York.

Road slides are a huge issue in this section of Erie County with at least four major failures in the past decade.

Albany, NY — One of the development companies owned by Republican candidate for governor Carl Paladino was hit with a felony charge and fined $ 500,000 a decade ago for failure to detect asbestos in a Syracuse bowling alley he was renovating and eventually razed.

MPs will admit to the failure of the war on drugs tomorrow, in one of the most important developments in the debate for a decade.

He told an audience at the Cooperative Bank that the Libor scandal has demonstrated the failures of Britain's economy «in the last decades».

Schneiderman's campaign also pressed Rice hard on a number of her negatives — most notably her failure to vote for close to two decades — and her camp was flat - footed in responding.

It is not, as some of Corbyn's detractors have claimed, the worst local election performance for decades (Ed Miliband's Labour did a little worse in 2011 and William Hague did significantly worse for the Tories in 1998) but it is the sort of local election performance heralding failure at the next general election.

Syracuse, NY — The state Thruway Authority agreed Monday to transfer 34 acres surrounding the Syracuse Inner Harbor to the city in hopes that it will overcome the state's decade of failure to redevelop the land into a recreational, residential and commercial attraction.

In my more than a decade of political commentary, I have informed and addressed the failures of elected officials and politicos of all Parties.

In my view, the most important omission related directly to science and technology aspects of the greenhouse gas issue is the failure to point out the tremendous opportunity that exists to limit warming over the next few decades by imposing strong, mandatory controls of short - lived warming agents (so methane, black carbon, and tropospheric ozone).

29 GENETICALLY MODIFIED SUPERHUMANS The debate over human germ - line engineering — reworking genes in the sperm and egg to create inheritable new traits — sputtered out early in the last decade after gene therapy had a series of notable failures.

Cardiovascular disease remains the number one cause of death in the Western world, with heart failure representing the fastest - growing subclass over the past decade.

After decades of failure, a new approach to negotiations has raised hopes that nations meeting in Paris will agree to meaningful climate steps.

A slew of emails stolen from the University of East Anglia's Climatic Research Unit highlight definite character flaws among some climate scientists — including an embarrassing attempt to delete emails that discussed the most recent report from the United Nations Intergovernmental Panel on Climate Change — while also exposing what looks like a failure of scientists to acknowledge a halt to global warming in the past decade.

They have generated excitement over the past few decades because scientists can study them in the laboratory to discover the genetic switches that control the development of specialized tissues in the embryo and fetus, and also because of their potential to replace body tissues that have broken down, such as pancreatic cells in those with diabetes or heart muscle cells in those with congestive heart failure.

In response to the 1993 failure of the Mars Observer mission — a billion - dollar, decade - in - the - making probe that mysteriously lost contact with ground controllers just before it was scheduled to go into orbit around the planet — NASA administrator Daniel Goldin decided to shift to smaller, less expensive spacecraft and create a sustained exploration campaign by sending one or two probes to Mars at every launch opportunitIn response to the 1993 failure of the Mars Observer mission — a billion - dollar, decade - in - the - making probe that mysteriously lost contact with ground controllers just before it was scheduled to go into orbit around the planet — NASA administrator Daniel Goldin decided to shift to smaller, less expensive spacecraft and create a sustained exploration campaign by sending one or two probes to Mars at every launch opportunitin - the - making probe that mysteriously lost contact with ground controllers just before it was scheduled to go into orbit around the planet — NASA administrator Daniel Goldin decided to shift to smaller, less expensive spacecraft and create a sustained exploration campaign by sending one or two probes to Mars at every launch opportunity.

Yet, thousands perished of starvation throughout the region and populations in Somalia, Kenya and elsewhere remain reliant on aid — a decades - long failure that also encompasses civil war and political instability.

(ORLINDA PLATERO) In Crownpoint, N.M., in 1999, Orlinda «Orie» Platero sat with her father as he slowly died from heart failure following decades of trouble that included bypass surgery 20 years earlieIn Crownpoint, N.M., in 1999, Orlinda «Orie» Platero sat with her father as he slowly died from heart failure following decades of trouble that included bypass surgery 20 years earliein 1999, Orlinda «Orie» Platero sat with her father as he slowly died from heart failure following decades of trouble that included bypass surgery 20 years earlier.

They say that low - fat weight - loss diets have proved in clinical trials and real life to be dismal failures, and that on top of it all, the percentage of fat in the American diet has been decreasing for two decades.

In just two decades, online dating has risen from being a shunned tool used only by those deemed to be social failures, to being a normal part of the modern social construct.

The Pentagon Papers are being exposed by the New York Times, detailing the plans for and failure of intervention in Vietnam over the course of decades.

Such well - documented failures as Nothing But Trouble (1991) and Cops and Robbersons (1994) became his crosses to bear during a decade that also saw the colossal failure of his Fox comeback variety show, which was canceled two months after it premiered in 1993.

The direct - to - the - screen movie musical (as opposed to the adapted play or remake) has been an endangered species for decades and the box office failure of Newsies back in 1992 nearly killed it.